Page 29 - 2023 Shimadzu Analytical and Measuring Instruments
P. 29
MALDI-Based Instruments
Matrix-Assisted Laser Desorption/Ionization Matrix-Assisted Laser Desorption/Ionization
Time-of-Flight Mass Spectrometer Time-of-Flight Mass Spectrometer
AXIMA Performance AXIMA Confidence / AXIMA Assurance Chromatography Systems
AXIMA Assurance Mass Spectrometry Systems
The AXIMA Performance is a high-performance MALDI-TOF mass This high-sensitivity, high-throughput mass spectrometer provides
spectrometer utilizing state-of-the-art high-energy MS/MS, delivering strong support for proteomics research. The AXIMA Confidence
unparalleled flexibility, in a robust and reliable research-grade system. achieves a mass resolution of 15,000, and is capable of high-sensitivity
Shimadzu’s proprietary (patented) curved-field reflectron (CFR) enables analysis thanks to high performance laser beam focusing. It is equipped Life Science Lab Systems
true high-energy CID-MS/MS with a laboratory frame collision energy of with Shimadzu's proprietary (patented) curved-field reflectron (CFR), so
20 keV. It is an extremely versatile and powerful system, integrating it can obtain PSD MS/MS spectra seamlessly from the low molecular
workflows for a diverse range of analytical needs. LC-MALDI software weight region to the high molecular weight region, with a single
allowing confident identification of off-line separated complex mixtures measurement. AXIMA Assurance is the sister instrument to the AXIMA
via automated MS/MS. Confidence, and is exclusively for linear mode.
Linear mode 1 to 500,000 Da AXIMA Confidence AXIMA Assurance
Mass range
Reflectron mode 1 to 80,000 Da Mass range Linear mode 1 to 500,000 Da 1 to 500,000 Da
Linear mode 5,000 Reflectron mode 1 to 80,000 Da –
Mass resolution Spectroscopy Systems
Reflectron mode 20,000 Linear mode 5,000 5,000
MS/MS function CID/PSD Mass resolution Reflectron mode 15,000 –
Mass accuracy Reflectron mode 5 ppm (internal standard) MS/MS function Available (PSD) –
Brochure No. MO300 Brochure No. MO305 MO304
AXIMA Application System MALDI Digital Ion Trap Mass Spectrometer
AXIMA for Microorganism Identification System MALDImini-1 Systems X-ray and Surface Analysis
This system combines the AXIMA mass spectrometer, which is optimal for Despite its light and compact shape, The MALDImini-1 is capable of Measurement Systems Environmental
microbial identification, with microbial identification software. When achieving MS analysis, making it suitable for a large number of
3
microbes are analyzed directly with MALDI-TOFMS, a peak pattern (mass applications. With its simple configuration and compact size, it is
spectrum) is obtained, indicating the molecular weights of characteristic possible to install the MALDImini-1 in places where mass analysis Systems Non-Destructive Inspection Material Testing and
microbial proteins. By comparing the results to a database constructed devices could not previously be used. The vacuum pumps are entirely
using approximately 40,000 mass spectra, more than 1,900 different types contained within the device. The MALDImini-1 can be installed
of microbes can be identified. The microbes can be analyzed directly, anywhere where there is an AC 100-120V power supply. By combining
without the need for gram staining, morphological determinations and a MALDI ion source with Digital Ion Trap (DIT) technology, it is possible
other pretreatment required by conventional microbial identification to carry out high-sensitivity MS analysis even on micro-quantity
n
methods (biochemical, culturing, and PCR). As a result, a microbial samples.
identification that would have taken several hours with conventional Mass range m/z 650 to 70,000
methods can be accomplished with this system in about 2 minutes, MS/MS mass range m/z 350 to 5,000 Measurement Systems Physical Properties
enabling high throughput analysis at a top speed of 1,000 samples per Mass resolution > 4,000 FWHM
day. In addition, since pretreatment reagents are not required, running MS n 1 ≤ n ≤ 3
costs are reduced to about half that for existing methods. Brochure No. C146-E395
Note: This system is not intended for use in clinical diagnoses. Use it only for research purposes.
29