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Liquid Chromatograph Mass Spectrometers /
Gas Chromatograph Mass Spectrometers
New Fully Automated Sample Preparation Module for LC-MS
CLAM-2040
Pave the way for the future
of clinical research.
Operational improvements in LC-MS systems have made LC/MS an
advantageous technique for clinical research, thanks to its specificity, its
accuracy and its capability to analyze several targets simultaneously. The
CLAM-2040 is an online automated sample preparation module that
brings LC-MS smoothly into your laboratory. The CLAM-2040
Mass Spectrometry Systems
accompanies you on most of the analytical workflow and improves your
overall throughput by drastically reducing the sample preparation time. Typical LC/MS analysis workflow in the clinical research laboratory.
Simply place the blood tubes in position and the CLAM-2040 performs
the next steps automatically, from sample extraction up to LC/MS Analysis Sample Sample preparation LC-MS/MS Data post- Review
registration
request
(option)
analysis and data processing. It can be connected to the LCMS- (LIS) and and transfer 10–60 min analysis processing and result
<1 min
2–5 min
9050/9030/8060NX/8060/8050/8045/8040 systems. sampling to the lab report (LIS)
Volume in preparation vial 350 μL maximum One result every 12 to 60 min.
Sample dispensing, reagent dispensing, shaking,
Preparation functions suction filtration and heating CLAM-2040 + LC/MS improved analysis workflow.
*Up to 20 steps can be set in a protocol.
Sample handling Multiple sample preparations overlap. Analysis Sample Sample Review
Onboard preparation vial request registration prep. 4 min LC-MS/MS Data post- (option)
capacity Up to 60 filter vials and 60 collection vials (LIS) and and transfer and up to analysis processing and result
sampling to the lab 3 samples 2–5 min <1 min report (LIS)
Note 1: LC and LCMS units are not included with this product. at once
Note 2: For Research Use Only. Not for use in diagnostic procedures.
Brochure No. C146-E469 These steps are managed by
the CLAM-2040 and LC-MS instrument.
One result every 2.6 min.
Product >
Gas Chromatograph Mass Spectrometer
Smart Solutions for Maximizing the Potential of
Laboratories
GC-MS systems, which are used in all sorts of fields, have now become a general purpose
tool for analysis. Consequently, customers are increasingly demanding GC-MS systems that
offer higher performance for the cost and enable a better work–life balance for operators.
The GCMS-QP2020 NX maximizes the potential of laboratories by offering efficiency
improvements for various aspects of analytical work.
Active Time Management Smart EI/CI Ion Source
Active time management helps visualize how much time was spent on The newly developed Smart EI/CI ion source can be used to acquire CI
maintenance, switching between systems, or performing analyses, for data without exchanging ion sources or losing the general applicability
example, to help manage the instrument downtime more appropriately. of EI sensitivity. With the EI mode, even if identification is difficult using
By automating tasks previously performed by users, it enables more a mass spectral library, molecular weight information can be collected
efficient system operation. from the CI mode data, which is especially useful for predicting
Automatic System Startup/Shutdown unknown compounds.
441 No ion source 441
100 EI 100 CI
75 57 replacement necessary 75
50 50 385 647
25 91 191 308385 25 106 329 483 591
0 0
250 500 250 500
Confirmation of Mass Spectrum Smart EI/CI ion source Confirmation of Molecular
Weight Information
EI data Based on the EI mass MW: 646
CI data spectrum and CI molecular
weight information, the
substance is presumed
to be tris(2,4-di-tert-
Automatic Tuning Decision-Making 5.0 7.5 10.0 12.5 15.0 17.5 20.0 22.5 butylphenyl) phosphite,
min m/z 441
Example of Analyzing Extract from a Packaging used as an oxidation
Container (Extracted with 20 % Ethanol) inhibitor.
Time Management for Continuous Analysis
Brochure No. C146-E367
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