Page 23 - Application Notebook - Solution for Food Safety

Application No.C136
News

n Conclusion n References
A fast, selective and highly sensitive method has been 1. Commission Regulation (EC). 2005. No 396/2005 of
developed for the quantitation of 646 pesticides using the European Parliament and of the Council, maximum
a single method with 1,919 transitions (corresponding residue levels of pesticides in or on food and feed of
to up to 3 MRM transitions per compound) and a LC plant and animal origin. Official Journal of the
gradient time of only 10.5 minutes. European Union, L 70: 1-16
As the LCMS-8060 has a rapid polarity switching time 2. US Environmental Protection Agency, Electronic code
of 5 msec, the single multi-residue LC/MS/MS method of federal regulation: Title 40: Part 180 - tolerances and
supported the analysis of 34 pesticides in negative ion exemptions for pesticide chemical residues in food.
mode and 612 compounds in positive ion mode. http://www.ecfr.gov/cgi-bin/text-idx?c=ecfr&tpl=/
ecfrbrowse/Title40/40cfr180_main_02.tpl
The enhanced performance and higher sensitivity of the
LCMS-8060 has created new opportunities in sample 3. Japanese Ministry of Health, Labour and Welfare,
dilution to reduce ion signal suppression and matrix Department of Food Safety. 2006. Director Notice
effects. For most compounds a dilution factor of 1:20 about Analytical Methods for Residual Compositional
or 1:50 was sufficient to provide recoveries in the range Substances of Agricultural Chemicals, Feed Additives,
70 - 120 %. and Veterinary Drugs in Food (Syoku-An No. 0124001
January 24, 2005; amendments May 26, 2006).

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