Page 19 - Application Notebook - PFAS Analysis

Application No. C184
News

two weeks’ investigation. The recovery of all PFAS covering the concentration range required by EPA 537,
compounds at the three concentration levels were well though the LCMS-8050 has a superior signal-to-noise
within the EPA’s CCC criteria (i.e. 70–130% of the true ratio as illustrated in Figure 3 (LCMS-8045) and
value). The data demonstrated that both the Figure 4 (LCMS-8050).
LCMS-8045 and LCMS-8050 were capable of reliably

LCMS-8045

PFOA PFOS
Q 412.90>369.00 (-) 9.10e3 Q 498.90>80.10 (-) 5.26e2
RT=10.860 RT=12.576
8.0e3
4.0e2
6.0e3

4.0e3
2.0e2
RT=12.055
2.0e3
RT=11.882
0.0e0 0.0e0
10.6 10.7 10.8 10.9 11.0 11.1 11.50 11.75 12.00 12.25 12.50 12.75
RT RT
Area Ratio Area Ratio
PFOA PFOS
11 2.0
10 1.8
9 1.6
8 1.4
7
1.2
6
1.0
5
0.8
4
0.6
3
0.4
2
1 0.2
0 0.0
0 1 2 3 4 5 6 7 8 9 10 0.0 0.5 1.0 1.5 2.0 2.5 3.0
Conc. Ratio Conc. Ratio
Figure 3. MRM chromatogram (for 1.25 ng/mL) and calibration curve for PFOA and PFOS using LCMS-8045
LCMS-8050

PFOA PFOS
Q 412.90>369.00 (-) 2.28e4 Q 498.90>80.10 (-) 4.29e3
RT=10.952 RT=12.687
4.0e3
2.0e4
3.0e3
1.5e4
1.0e4 2.0e3
5.0e3 1.0e3 RT=11.972 RT=12.148

0.0e0 0.0e0
10.6 10.7 10.8 10.9 11.0 11.1 11.50 11.75 12.00 12.25 12.50 12.75
RT RT
Area Ratio Area Ratio
8
PFOA PFOS
4.5
7
4.0
6
3.5
5 3.0
4 2.5
2.0
3
1.5
2
1.0
1
0.5
0 0.0
0 1 2 3 4 5 6 7 8 9 10 0.0 0.5 1.0 1.5 2.0 2.5 3.0
Conc. Ratio Conc. Ratio
Figure 4. MRM chromatogram (1.25 ng/L) and calibration curve for PFOA and PFOS using LCMS-8050