Page 18 - 2023 Shimadzu Analytical and Measuring Instruments

Liquid Chromatograph Mass Spectrometers
New Liquid Chromatograph Mass Spectrometer

LCMS-2050

SIMPLY EFFORTLESS

The LCMS-2050 is a single quadrupole liquid chromatograph mass
spectrometer (LC-MS) that is easy to use, high in basic performance,
and compact. The LabSolutions LCMS workstation for the LCMS-2050
delivers streamlined instrument control and sophisticated data analysis
using Analytical Intelligence. It also foresees and addressees the increase
in demand for energy savings.
Mass range m/z 2 to 2,000
Resolution 0.7 u
Scan speed Max. 5,000 u/sec
Mass Spectrometry Systems
Positive–negative ion polarity switching time 10 ms
Note: LC units are not included with this product.
Brochure No. C146-E442 Movies >

Seamless integration with LC by design Superior detection for added confidence
Nexera series We pursued ease of use as an LC detector in all Inheriting Shimadzu’s patented technology, the
aspects of the instrument design, instrument versatile LCMS-2050 delivers excellent data
control, and analysis data. As with other LC quality. The LCMS-2050 provides the world’s
detectors, It can be integrated into any fastest* performance, with a scan speed of
Shimadzu LC architecture, whether it is a 15,000 u/sec and a positive/negative ion switching
high-throughput analytical system, a speed of 10 msec. Thanks to the sufficient
preparative LC with fraction collection, or even sampling rate, the instrument reliably captures
a legacy model. And it as simple to use as other sharp UHPLC peaks. The LCMS-2050 is equipped
LC detectors. Only the simplest of acquisition with the newly developed Heated Dual Ion Source
parameters are required to obtain reliable and (Heated DUIS) as the standard configuration. This
sensitive detection. The LCMS-2050 has a new hybrid source combines the benefits of
“Mass- it” function that automatically overlays electrospray ionization (ESI) and atmospheric pressure chemical
LCMS-2050
mass information on chromatograms obtained ionization (APCI), two orthogonal techniques widely used in mass
by an LC detector. This function reduces the spectrometry. The result is excellent sensitivity achieved for compounds
trouble of comparing LC and MS for a diverse range of chemical properties, including low-polarity
chromatograms and the risk of missing data. compounds such as quintozene, which can not be detected with ESI but
can be detected at high sensitivity with the heated DUIS.
* As of June 2022, according to a Shimadzu survey

Conventional ESI Heated DUIS
Int. ×100,000 m/z 273.9 Int. ×100,000 m/z 273.9
1.0 1.0

0.5 0.5
0.0 0.0
Mass-it function 1.0 2.0 min 1.0 2.0 min
Mass chromatogram of quintozene
Streamlined operation for cost efficiency
Equipped with eco-friendly functions, it reduces energy by 43% 100
compared to the LCMS-2020. It is certified as “Eco-Products Plus,” 80
Shimadzu’s original environmentally conscious product designation. The Power consumption (%) 60
system not only limits running costs during analysis, but contributes to 40 Approx. 43%
realizing a carbon-free society by limiting CO 2 emissions. 20 0 Reduction
Shimadzu Conventional LC-MS LCMS-2050
Comparison of Power Consumption
This product is certified as Shimadzu’s Eco-Products Plus.
Reduced power consumption by 43% compared with Assumptions: the ecology mode detects idle times and automatically shuts down the system
conventional Shimadzu’s products. (vacuum not stopped) for 8 h/day on average, including 2 h/day during working hours; for 2
days/week, the instrument, including the vacuum, is fully shut down.

Automated support functions utilizing digital technology, such as M2M, IoT, and Artificial Intelligence (AI), that enable higher productivity and maximum reliability. Allows a system
to monitor and diagnose itself, handle any issues during data acquisition without user input, and automatically behave as if it were operated by an expert. Supports the acquisition
of high quality, reproducible data regardless of an operator’s skill level for both routine and demanding applications.
18