Page 13 - Shimadzu Nexera X2

Outstanding Expandability Broadens Applicability

UHPLC/HPLC Switching System Allows a Single System to Handle Both UHPLC and HPLC
This system is especially useful for users that want to quickly develop methods with
UHPLC and then deploy those methods horizontally to existing HPLC systems. By using a
flow line switching valve to automatically switch between dedicated UHPLC and HPLC
mixers, a single LC system can be used for both UHPLC and HPLC applications, thus
reducing the costs of introducing and maintaining additional systems.

Conventional column
Conventional mixer Flow line during conventional analysis

UHPLC
mixer

Flow line during UHPLC analysis
UHPLC column
Note: System configuration example

130 MPa Pressure Capacity of the Flow Line Switching Valve Accommodates a Wider Range of Applications

The 130 MPa capacity FCV-32AH flow line switching valve employs the same
high-pressure-resistance technology as autosamplers, so it can be used for a wide range of
applications, from UHPLC to HPLC. Since the FCV-32AH can be installed inside column ovens
or connected to systems externally, it is useful for a broad range of applications, such as
column switching or 2-dimensional LC.

Mixture
e
High-Efficiency Gradient Mixers Ensure Reliable Mobile Phase Mixture
The Nexera X2 systems feature microreactor type gradient mixers that are able to mix small quantities of mobile phases with high
efficiency. In addition to a 20 µL mixer that is ideal for MS front-end LC units and a 180 µL mixer that offers maximum mixing
efficiency, 40 µL and 100 µL models are also available that these provide a balance between mixing performance and gradient
delay, allowing you to select an optimal capacity.

Using the MR180 µL II

Mixer Models
MR 20 µL
MR 40 µL
MR 100 µL
MR 180 ll µL
Simple mixing using a T-joint

Achieves a baseline with minimal undulations, even for concentrated buffer solutions.

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