Page 11 - Shimadzu Nexera X2

A New Standard Nexera X2 System

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Nexera Quaternary System Enables Low-Pressure Gradient Analysis Using Four Solvents — Useful for Method Development
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ing Four Solvents — Use
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The Nexera Quaternary system is able to deliver low-pressure
gradient mixtures of four solvents. Its ability to load up to four
types of mobile phases in a single solvent delivery unit eliminates
the time and trouble of exchanging mobile phases during method
development. If a low-pressure gradient unit is added to a system
with two solvent delivery units, then both binary and quaternary
capabilities can be achieved in a single system, which can help
improve instrument utilization efficiency.

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Smooth Migration from General-Purpose HPLC Systems
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The Nexera X2 offers both UHPLC and HPLC capabilities with a
single system. Basic Nexera Quaternary system configurations with
one solvent delivery unit are capable of gradient analysis using up
to four solvents. Furthermore, existing HPLC methods can not only
be reproduced on the system, but also migrated to UHPLC
methods.
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Analytical Conditions
Column Shim-pack VP-ODS (150 mmL. × 4.6 mmI.D., 4.6 µm)
Flow rate 1.0 mL/min (gradient elution)

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Up to 16 Possible Mobile Phase Combinations

If a Nexera Quaternary system equipped with two solvent delivery units is available, then four different mobile phases can be loaded for
each solvent delivery unit, which means a maximum of 16 mobile phase combinations can be considered. Since that eliminates the
manual operations needed to exchange mobile phases each time mobile phase conditions are changed, it can reduce the amount of
labor hours required to prepare mobile phases.

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D
Solvent Delivery Unit 1
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B
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C
D Solvent Delivery Unit 2

16
16 mobile phase combinations
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