Page 8 - Shimadzu Nexera XS inert

Full-range of Bio-inert UHPLC Capabilities

The Nexera XS inert system eliminates the risk of sample adsorption or surface corrosion, while still providing all the Finger-Tightened Fittings for Simple and Secure Connections
exceptional features of the Nexera series, making it the perfect solution for a wide variety of applications.
Nexera XS inert systems feature tubing connections with unique finger-tightened fittings. They can achieve joints with
up to 105 MPa of pressure capacity by finger-tightening and without creating any dead volume.

Nexera XS inert combines excellent resistance to corrosion
with the inertness of surfaces in contact with the sample
and mobile phases. The system provides excellent
chromatographic separation performances for a wide
range of applications.

System Controller
SCL-40, CBM-40/40lite
Used to coordinate actions of the overall system, this
controller offers intuitive operation that minimizes
the stress involved in operating the system, from Flow Channel Switching Valves for Metal-absorbing Compounds
startup to shutdown.
All valves used in Nexera XS inert systems are designed to inhibit metal adsorption. That ensures worry-free switching
between multiple columns for method development or even for trap-and-elute analysis without being concerned
Detector about adsorption.
SPD-40/40V/M40
Inert type cells for UHPLC analysis eliminate the risk of FCV-0206H2i
adsorption on the detector. Low-diffusion cell, which 2-Position/6-Port Valve
Columns
has 5 mm of optical path length, can also be selected.
Solvent
delivery unit
Detector
Solvent Delivery Unit
Used to automatically switch between
LC-40D XSi columns and detectors.
Flow line switching unit Auto Sampler
Designed with corrosion-resistant non-stainless steel (Built into solvent delivery unit)
materials, it offers rugged, low-pulsation perfor- FCV-0607H2i
mance, advanced AI features and solvent blending 6-Position/7-Port Valve
Flow line switching valve
capabilities. (optional). Solvent
delivery unit Column oven

Autosampler Method Scouting System
SIL-40C XSi Used to switch between up to six Flow line switching unit
columns for method development. (Built into solvent delivery unit)
This high-performance autosampler features non-
metal materials for all surfaces that contact liquids.
That inhibits metal-adsorption of biomolecules.

Mobile Phase pH Monitor: pHM-40 (optional)
UHPLC Inert Switching Valve
In the case of Ion-exchange chromatography or size-exclusion chromatography used for
FCV-0206H2i/FCV-0607H2i
the analysis of proteins or other biomolecules, the mobile phase pH can strongly affect
Designed with adsorption-inhibiting materials for all
chromatographic separation. The pH monitor pHM-40 continuously monitors the pH of
wetted surfaces (refer to p. 9).
mobile phases to identify any changes in mobile phase pH in real time.

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