Page 13 - Shimadzu Nexera XS inert

Nexera Series Features for Auto-Diagnostics and Recovery

Assisting Analytical Operations In rare cases, air bubbles can form in the mobile phase and cause problems if inhaled into the pump. Nexera has the

ability to monitor baseline changes and pressure fluctuations to check for abnormalities. When it detects an unusual
fluctuation, it can automatically pause the analysis, purge the flow path, and restart analysis once it has confirmed
The same outstanding instrument performance capabilities offered by Nexera series systems are also available in recovery to normal pressure.
Nexera XS inert systems. For a more advanced analysis, Nexera XS inert can be used with Analytical Intelligence
Pressure
technology for automatic analysis.
Auto-Diagnostics for
Trapped Bubbles (patented) Fluctuation detected
If an air bubble becomes trapped in the pump Normal analysis Auto-purge Resume analysis
once stable
Stable Baseline head, it causes an abrupt drop in pressure, after
which periodic pressure changes (pulsations) will
Baseline fluctuations can affect peak Room Temp. Area %RSD occur. This can be detected using Shimadzu's
25 °C (n=20) proprietary bubble detection algorithm which
area calculations, reducing the accuracy 20 °C 0.62% Sample 1 Sample 2 Sample 2
mAU assesses these distinctive pressure fluctuations (Failure) (Retry)
of quantitative results. The SPD-M40 2.5 SPD-M40
0 caused by trapped bubbles to distinguish them
photodiode array detector's "Advanced -2.5 from any expected changes in pressure.
TC-Optics" function adjusts the -5.0
-7.5 Area %RSD
temperature of the flow cell, lamp, and -10.0 Another Vender’s (n=20)
-12.5 1.87%
optical system to lessen the impact of PDA Detector
0 50 100 150 200 250 min
external temperature changes. Noise Mobile Phase Levels Measured in Real Time
Room Temperature vs PDA Baseline
and drift have also been reduced by
(Comparison to Comparable Non-Shimadzu Model)
40% compared to the previous model. Reservoir tray weight sensors (optional) can be used to monitor the volume of the mobile phase or autosampler rinse
solution in up to twelve* containers. The containers can also be checked remotely from a smart device. You will no
longer need to worry about running out of mobile phase mid-analysis, because the device will notify you before
Advanced TC-Optics (SPD-M40) (patented) Heat discharged starting the run if the volume remaining is too low.
Heat removal
With the SPD-M40, in addition to conventional cell temperature mechanism *Up to 12 solutions can be monitored using 1-liter containers or up to 4 solutions using larger containers (2-liter or up to 5-liter containers).
regulation, the lamp and spectrometer, which are responsible for
thermal effects on absorbance, are also thermally regulated,
Monochromator
further reducing baseline fluctuations caused by the light source. Light Comparing Solvent Volume Measurements with Predicted Consumption (patented)
source
lamp Cell
Triple The required mobile phase volume is predicted at the start of analysis from the weight sensor's measurement data, the
temperature-control instrument configuration information (the mobile phase used and the rinsing liquid configuration), and the analysis
method. If a shortage is expected, the user will be notified.

Proprietary Structure for Ensuring Sample Cooling

SIL-40 series autosamplers include a direct-access function that helps improve analytical operating efficiency by allowing
additional sample vials or MTP plates to be inserted even during data acquisition. A dry air flow control system ensures
reliable sample cooling and relieves operators from the inconvenience of dealing with condensation water.

Dry Air Flow Control (patented)
The sample rack serves the role of
Minimizes sample temperature changes
Room
controlling the flow of cooling air temperature
inside the autosampler. Even if the Dry cooling air flow air Monitoring Levels Even from Outside the Laboratory
sample rack is pulled out, ingress of
external air is prevented to inhibit • Automated support functions utilizing digital technologies, such as M2M, IoT, and Artificial Intelligence (AI),
that enable higher productivity and maximum reliability.
the formation of condensation
• Allows a system to monitor and diagnose itself, handle any issues during data acquisition without user input,
inside the autosampler or any sharp and automatically behave as if it were operated by an expert.
Changes the direction of air circulation
increases in sample temperature. • Supports the acquisition of high quality, reproducible data regardless of an operator's skill level for both
routine and demanding applications.

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