Page 15 - Shimadzu Nexera XS inert

Quickest Way to Results

Automates Development of Analytical Conditions Unique Functionality Reduces Data Analysis Work

Method Scouting i-PeakFinder ™

The process of considering which analytical conditions to specify for LC separation requires evaluating a huge number of The process of identifying peaks obscured by baseline undulations or noise, identifying shoulder peaks with inade-
possible combinations of columns, mobile phases, column temperatures, and other factors, which can be taxing on quate separation, and so on, can be very tedious and produce results that vary depending on skill level. Shimadzu's
analytical personnel. The Nexera method scouting system offers functionality for automatically switching between multiple unique i-PeakFinder peak integration algorithm is perfect for accurately detecting peaks in troublesome chromatograms.
mobile phase conditions and columns for analysis. Consequently, it can be used to develop methods more efficiently by
automating the process of optimizing mobile phase pH, salt concentration, or other analytical condition settings.
Baseline Processing = No Setting Baseline Processing = Vertical Division

Previous Method Aggregate Monomer Fragments Aggregate Monomer Fragments

Create method Create schedule Acquire data Analyze data

A method must be created for each combination of
column and mobile phase. Creating this large number
of methods is labor-intensive.
The operation is complicated because a large
amount of data is manually combined into
Column 3
one report. 12.0 14.0 16.0 min 12.0 14.0 16.0 min
Column 1
Column 5
Column 6
Column 2
Column 4
Overnight
Overnight
Method Scouting System + LabSolutions MD
Set conditions Create schedule Acquire data Analyze data
automatically
Methods are automatically created Carefully Selected Functionality for Supporting Data Analysis
with different combinations of
columns, mobile phases, etc.
™
Templates are output Print out LabSolutions Insight Software for LC/MS Data Analysis
after being auto- as a 1-page
Column 4
Column 6
Column 5
Column 3
Column 1
Column 2
matically filled with report.
analytical results. This dedicated LC/MS analysis software features functionality that provides powerful support for multiple-component
and multi-sample data analysis, such as functionality for flagging, filtering, and peak comparison.
mAU
2
pH 5.7
0
85% A
2
10% B pH 6.0
X
5% C 0
2
0% D Solvent pH 6.3
delivery unit 1
0
50%
A Mixer 2
20% pH 6.6
B
Y 0
5% C
2
25% D Solvent pH 6.9
delivery unit 2
0
Solvent Blending Binary Gradient 2
pH 7.2
Mobile phases prepared Gradient analysis 0
automatically at each pump with mobile phases 0.0 2.5 5.0 7.5 min
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