Page 30 - Application Notebook - PFAS Analysis
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SSI-LCMS-102
■ Summary and Conclusions
The Shimadzu LCMS-8045 exceeds the performance
criteria specified by EPA Method 537.1 for all specified
compounds. Method detection limits ranging from 0.48 to
1.64 ppt were obtained with recoveries of at least 80% for
all compounds. The Shimadzu LCMS-8045 achieves rapid,
reliable and highly sensitive quantitation of PFAS in
drinking water by method 537.1. The LCMS-8045 can
easily be upgraded to a LCMS-8050 or a LCMS-8060 for
improved method detection limits. A 5 uL injection volume
was used in contrast to the 10 uL injection described in
EPA Method 537.1, making the method more robust and
reducing long-term cost of ownership.
■ References
1. US EPA. Method 537.1, Detections of Selected Per- and Polyfluorinated Alkyl Substances in Drinking Water by
Solid Phase Extraction and Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS). Version 1.0,
November 2018 https://www.epa.gov/water-research/epa-drinking-water-research-methods
2. Environmental Science and Technology. “Polyfluorinated Compounds: Past, Present, and Future”
http://www.greensciencepolicy.org/wp-content/uploads/2014/10/Lindstrom-Strynar-and-Libelo-2011.pdf
3. US EPA. Basic Information about Per- and Polyfluoroalkyl Substances (PFAS). https://www.epa.gov/pfas/basic-
information-about-and-polyfluoroalkyl-substances-pfass
4. US EPA. Drinking Water Health Advisories for PFOA and PFOS. https://www.epa.gov/ground-water-and-drinking-
water/drinking-water-health-advisories-pfoa-and-pfos