Page 13 - LifeScience Solution for FNIRS

For Research Use Only. Not for use in diagnostic procedures.

Simultaneous Measurement with EEG Light to Measure Brain Function Principle of Using Near Infrared

Data Imaging Optical Brain-Function

Application Example of Simultaneous Measurement with Electroencephalography (EEG) Stim. Stim.
EEG Measurement Range
More recently, to take advantage of superior spatial and temporal resolution characteristics, there has been interest in simultaneous P22 P47 P22 P47
measurement methods that combine noninvasive brain measurement methods.

Simultaneous measurement with fNIRS and EEG was used to investigate the relationship between neural activity and the bilitation Neuroreha-
hemodynamic response of the somatosensory cortex to electric stimulation of the median nerve*.

* The median nerve extends from the brachial plexus and runs roughly down
the center of the abdominal side of the upper extremities.

The whole-head holder (Fig. 1) includes EEG sockets ( ) located fNIRS and fMRI Comparison of
midway between the NIRS transmitter and receiver probes ( )
to align the NIRS channels (measurement points) with the
position of EEG probes (Fig. 2a and 3a). Motor Control Brain Activity during

Fig. 3a Measurement Range of EEG Probes (32 channels) Fig. 3b Somatosensory Evoked Electric Potential
in Response to Electric Stimulation Measurement with EEG Simultaneous

Fig. 1 Relative Positions of NIRS and EEG Probes Analysis Method NIRS Signal

NIRS Measurement Range

0 sec 1 sec 3 sec 5 sec Inner Speech Investigating
Fig. 4 Brain Activity at Indicated Time (sec) Intervals After Electric Stimulation
Of all the locations where Oxy-Hb (Fig. 2b) and somatosensory evoked electric potential (Fig. 3b) were measured, the somatosensory
evoked potential at P22 (positive wave at 22 ms of latency) increased in the primary somatosensory cortex of the ear (left) on the
opposite side from the side that was electrically stimulated (Fig. 3a and 3b). Functions Language Processing
In addition, Oxy-Hb increased in the primary somatosensory cortex of the opposite ear from the electrical stimulation 5 seconds after
the electrical stimulation (Fig. 4).
Simultaneous measurement using NIRS and EEG is especially effective for investigating the correlation between hemodynamic response
and neural activity.

(Data provided by: Mr. Hisao Nishijo, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama) Research Mental Disorder
Transmitters : Boxes containing blue numbers Reference: Takeuchi., M, Hori, E., Takamoto, K., Tran, A.H., Kohno, S., Ishikawa, A., Ono, T., Endo, S. and Nishijo, H. (2009)
Receivers : Boxes containing red numbers "Brain cortical mapping by simultaneous recording of functional near infrared spectroscopy and electroencephalograms from the whole brain during
Measurement Channels : Blue numbers
Special Channels : Red numbers right median nerve stimulation." Brain Topogr, 22, 197–214.

Fig. 2a Measurement Range of Transmitter and Fig. 2b Change in Oxy-Hb in Response Shimadzu fNIRS Key References Regarding
Receiver Fibers (103 channels) to Electric Stimulation

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