Page 215 - Shimadu Consumables Catalog

Micro Solid Phase Extraction Syringe MEPS™

MEPS™ is Micro Extraction by Packed Sorbent and is used for sample preparation and handling. MEPS is the miniaturization of
conventional SPE packed bed devices from milliliter bed volumes to microliter volumes. The MEPS approach to sample preparation is
suitable for reversed phases, normal phases, mixed mode or ion exchange chemistries. MEPS is available in a variety of common SPE
phases.

Meps Barrel Insert And Needle

SAMPLE SIZE AND SENSITIVITY FLEXIBLE AND EASY TO USE
Sample volumes may be as little as 10 μL, or by taking multiple The dimensions of the sorbent bed ensure performance remains
aliquots of 100 μL or 250 μL, samples of 1 mL or larger may be identical to conventional SPE devices when used for extraction of
concentrated. similar samples. The AOC-MEPS system was developed to incorpo-
rate MEPS into a process automation workflow, combining sample
AUTOMATION preparation and analysis in a single platform.
Extract samples and make injections on-line using a single device,
reducing sample processing times and the need for operator inter-

vention. AOC-MEPS System
SORBENT LIFE
BIN life is dependent on the specific matrix being analyzed. For
example, C18 analysis of whole plasma samples is conservatively 25-
100 samples before the BIN needs to be changed. BIN life of cleaner
samples is significantly longer.

Chromatogram of 22 pesticides standard solution (40 ng/mL)

When automated by an AOC-MEPS system, the injection volume is
much larger compared to the commonly used GC injection volumes
of 1 - 2 μL. With AOC-MEPS, the typical injections are 50 to 200 μL
of elution solvent.
A large volume injection technique that removes the solvent
volume from inside the injector unit while condensing the target
compounds should be employed.

CARRYOVER
The small quantity of phase in the MEPS BIN is easily and effectively
washed between samples to reduce the possibility of carryover.
This washing process is not practical with off-line SPE devices. With
automated MEPS, washing occurs while the previous sample is
running.

Pg C-65