Page 32 - Application Notebook - Solution for Food Safety

C146-E306

For LabSolutions Version 5.82 and Later

LC/MS/MS Method Package

for Residual Pesticides Ver. 2

・ W orld’ s largest compound panel (646 pesticides in a
W
World’s largest compound panel (646 pesticides in a
orld’
s largest compound panel (646 pesticides in a
single method)
single method)
single method)
・ Ultra-high-speed method, with detection in 10.5 minutes
Ultra-high-speed method, with detection in 10.5 minutes
Ultra-high-speed method, with detection in 10.5 minutes
・ Ultra-high-speed detection delivers robust and reproducible
Ultra-high-speed detection delivers robust and reproducible
Ultra-high-speed detection delivers robust and reproducible
data quality for extended pesticide programs
data quality for extended pesticide programs
data quality for extended pesticide programs
・ Pretreatment program to improve the shape of peaks for
Pretreatment program to improve the shape of peaks for
Pretreatment program to improve the shape of peaks for
polar pesticides
polar pesticides
polar pesticides
・ Excellent data stability in combination with the
Excellent data stability in combination with the
Excellent data stability in combination with the
LCMS-8000 series
LCMS-8000 series
LCMS-8000 series
LCMS-8060
Pesticide Screening Analysis for 646 Pesticides in 10.5 Minutes
Using this method package in combination with the 10 6 • Three MRM transitions for over 99% targeted pesticides (1,919 transitions in total)
2.00 • A class-leading polarity switching time of 5 msec
LCMS-8050/8060 enables performing a pesticide analysis of
646 pesticides in 10.5 minutes. 1.75
Since the LCMS-8050/8060 have a rapid polarity switching time 1.50
of 5 msec, a single multi-residue LC/MS/MS method supports
the analysis of 612 pesticides in positive ion mode and 34 1.25
compounds in negative ion mode (Three MRM transitions for
1.00
over 99% targeted pesticides, resulting in 1,919 transitions in
total). 0.75
0.50
0.25
MRM Chromatograms for 646 Pesticides Spiked into a Mint Extract at 0.01 mg/kg
0
0.0 1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0 9.0 10.0 min
Maintains High Data Quality Even with High-Speed Analysis 3.00 x10 6
• 25 pesticides eluting over a 9 time window 75 msec (16%)
The LCMS-8050/8060 delivers exceptional sensitivity and enhanced capability in 2.75 • Peak area variation for 25 components 10 msec (2%)
(%RSD, n = 6): 1.1-5.9 %RSD
pesticide screening. By developing unique technologies for fast data acquisition, 2.50
the LCMS-8050/8060 systems create new opportunities for high data density 2.25 Loop Time: 460 msec
375 msec
analysis and expanded pesticide screening programs. For example, the peak area 2.00 (82%)
variation for 25 pesticides eluting over a nine-second time window (6.45-6.60 1.75 Polarity Switching Time
minutes) spiked into a mint matrix extract at the reporting limit of 0.01mg/kg Pause Time
1.50 Dwell Time
varied between 1.1-5.9% (%RSD; n=6).
1.25
1.00
0.75
MRM Chromatograms for 25 Components Detected with Retention Times of 6.45 to 6.60 Minutes 0.50
(Three MRM Events Per Compound, One Polarity Switching) and 0.25
Ratio of Dwell Time (green), Pause Time (red) and Polarity Switching Time (blue) in 460 msec of 0.00
Loop Time When 25 Pesticides are Simultaneously Monitored (Top right) 6.25 6.30 6.35 6.40 6.45 6.50 6.55 6.60 6.65 6.70 6.75 min