Page 25 - Clinical-Medical Solution for Clinical Chemistry

High-sensitivity and simultaneous analysis of Psychoactive drugs
using LC-MS/MS with full-automated pretreatment system

Concentration in sample Serum Whole blood Urine
( g/mL) 0.01 0.1 1 0.01 0.1 1 0.01 0.1 1
Alprazolam 69% 70% 82% 78% 75% 86% 98% 93% 106%
Bromazepam 73% 74% 78% 82% 76% 77% 103% 96% 112%
Brotizolam 72% 72% 86% 79% 73% 85% 98% 93% 108%
Chlordiazepoxide 76% 73% 81% 77% 73% 82% 99% 93% 111%
Clorazepic acid 84% 70% 80% 78% 77% 90% 97% 91% 126%
Clotiazepam 73% 73% 74% 81% 76% 85% 96% 93% 116%
Cloxazolam 90% 79% 82% 81% 80% 89% N.A 77% 83%
Diazepam 82% 77% 77% 80% 74% 83% 96% 94% 109%
Estazolam 72% 73% 79% 80% 74% 82% 99% 95% 110%
Ethyl lo azepate 82% 72% 81% 76% 73% 80% 90% 92% 112%
Etizolam 77% 73% 80% 81% 75% 95% 105% 95% 103%
Fludiazepam 79% 76% 79% 74% 74% 87% 95% 93% 115%
Flunitrazepam 79% 74% 80% 76% 73% 82% 100% 95% 111%
Flurazepam 75% 73% 93% 73% 73% 97% 92% 93% 99%
Flutazolam 75% 71% 79% 70% 70% 81% 92% 97% 111%
Flutoprazepam 82% 79% 73% 79% 77% 92% 96% 89% 106%
Haloxazolam 56% 64% 87% 55% 68% 75% 86% 89% 122%
Lorazepam 76% 73% 76% 86% 70% 76% 115% 85% 103%
Lormetazepam 75% 73% 78% 75% 73% 79% 95% 89% 106%
Medazepam 80% 70% 79% 77% 76% 91% 96% 90% 123%
Mexazolam 81% 77% 73% 83% 75% 103% 79% 93% 123%
Midazolam 74% 70% 80% 79% 72% 84% 94% 91% 104%
Nimetazepam 75% 73% 81% 76% 75% 85% 105% 98% 115%
Nitrazepam 80% 73% 77% 75% 74% 77% 97% 93% 107%
Oxazolam N.A. 73% 89% N.A. 73% 88% 77% 70% 81%
Prazepam 78% 82% 73% 81% 78% 86% 94% 90% 107%
Quazepam 73% 78% 70% 81% 77% 81% 86% 88% 217%
Rilmazafone 78% 76% 82% 71% 73% 70% 98% 97% 126%
To sopam 73% 71% 82% 78% 75% 85% 101% 93% 109%
Triazolam 72% 70% 83% 80% 76% 85% 93% 93% 110%
Zolpidem 71% 72% 87% 76% 74% 95% 99% 97% 102%
α-Hydroxyalprazolam 84% 70% 76% 81% 72% 77% 96% 95% 110%
α-Hydroxybrotizolam 70% 74% 79% 74% 70% 76% 94% 89% 107%
α-Hydroxyetizolam (M-VI) 79% 70% 79% 71% 70% 80% 86% 90% 104%
7-Amino unitrazepam 75% 72% 78% 79% 75% 79% 94% 91% 108%
7-Aminonimetazepam 75% 74% 78% 81% 75% 80% 93% 90% 104%
7-Aminonitrazepam 74% 71% 78% 77% 73% 88% 94% 90% 103%
α-Hydroxytriazolam 74% 72% 78% 79% 75% 79% 109% 92% 106%
Zolpidem M-1 74% 71% 86% 76% 74% 95% 99% 98% 103%

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