Page 24 - Clinical-Medical Solution for Clinical Chemistry

High-sensitivity and simultaneous analysis of Psychoactive drugs
using LC-MS/MS with full-automated pretreatment system

Concentration in sample Serum Whole blood Urine
( g/mL) 0.1 1 10 0.1 1 10 0.1 1 10
Allobarbital (neg) 81% 84% 80% 67% 77% 76% 90% 103% 89%
Amobarbital (neg) 81% 86% 80% 78% 79% 78% 88% 103% 92%
Barbital (neg) 84% 82% 91% 73% 84% 79% 87% 102% 89%
Pentobarbital (neg) 77% 78% 80% 72% 80% 76% 95% 109% 92%
Phenobarbital (neg) 77% 83% 92% 70% 74% 81% 92% 101% 86%
Secobarbital (neg) 69% 92% 80% 67% 73% 77% 78% 107% 88%
Thiamylal (neg) 76% 83% 84% 72% 79% 77% 76% 97% 84%
Thiopental (neg) 75% 84% 81% 68% 75% 77% 81% 110% 95%
Bromovalerylurea 71% 84% 84% 75% 79% 79% 91% 104% 92%

Concentration in sample Serum Whole blood Urine
( g/mL) 0.01 0.1 1 0.01 0.1 1 0.01 0.1 1
Amitriptyline 74% 69% 80% 64% 66% 70% 87% 84% 102%
Amoxapine 72% 73% 80% 66% 66% 73% 90% 86% 101%
Clomipramine 67% 70% 74% 63% 65% 83% 82% 78% 99%
Desipramine 74% 72% 77% 57% 60% 89% 90% 83% 103%
Dosulepin 70% 68% 80% 63% 64% 77% 88% 86% 100%
Imipramine 76% 70% 81% 64% 67% 87% 86% 84% 100%
Maprotiline 68% 68% 76% 56% 58% 67% 91% 83% 101%
Mianserin 79% 84% 76% 78% 77% 81% 90% 85% 111%
Nortriptyline 71% 73% 80% 55% 64% 70% 91% 83% 100%
Promethazine 71% 69% 80% 89% 104% 116% 89% 84% 103%
Setiptiline 83% 75% 83% 68% 70% 83% 87% 87% 106%

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