Page 18 - Shimadzu’s Solutions for Impurities Analysis

FDA Regulations on Qualitative and Quantitative Analysis
Inorganic Impurities
of Inorganic Impurities
Atomic Absorption Spectrophotometer

˙ Inorganic Impurity Analysis Using an Atomic Absorption
Spectrometer

Inorganic impurities are one class of impurity in of inorganic impurities in pharmaceutical products. The
pharmaceutical products listed in the ICH guidelines. AA-7000 Atomic Absorption Spectrophotometer is effective
Inorganic impurities include metal from metal catalysts or for the trace analysis of hazardous elements such as cadmium
manufacturing equipment used for the synthesis of the and arsenic. Determination of lead in refined white sugar is a
pharmaceutical ingredients. Atomic absorption typical example of this analysis.
spectrophotometry is a method for the quantitative analysis
FDA Regulations on
Genotoxic Impurities
˙ The AA-7000 Features

Incorporates newly developed 3D optical system. The optical
ɾ
double-beam photometric system is automatically set for
flame measurements and the high-throughput single-beam
photometric system for furnace measurements. The optical
system has been designed to produce its maximum
performance for each measurement method through
optimal adjustment of the light beam and by using a light
beam digital filter and optical components that restrict light
Residual Solvents
losses.
FDA Regulations on
Advances in the optical system and a new graphite furnace
ɾ
design achieve improved lower limits of detection for
furnace analysis (comparison with Shimadzu products).
Condition Setting Screens
ɾ
Digital temperature control and gas flow rate control
enhance reproducibility. As a result, the AA-7000 achieves
superb analysis performance in many fields.
Select the ideal model for the target application: flame-only
type with a short measurement time, furnace-only type ideal
for trace analysis, or the dual-atomizer system with
automatic flame/furnace switching.
A single autosampler supports the dual flame/furnace type.
ɾ
Inorganic Impurities
FDA Regulations on

Operation Screen

WizAArd
AA-7000
Workstation for AA
Atomic Absorption Spectrophotometer
Support from Shimadzu

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