Page 3 - LC-SFC_Pharma_Brochure
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Enhanced Pharmaceutical LC & SFC Workflows
SOLUTION 3:
SOLUTION 1: SOLUTION 2:
LC METHOD LC METHOD SAMPLE
DEVELOPMENT TRANSFER PREPARATION
& PURIFICATION
Method Scouting System automatically New UHPLC/HPLC dual- ow LC A range of con guration options for
screens for the best combination of system preparative and puri cation
mobile phases and column chromatography
Easy implementation and one-click
Minimize the time needed for method transfer of chromatographic Obtain higher compound purity and
development without compromising methods between di erent LC faster puri cation e ciency than
the quality instruments traditional methods
DATA INTEGRITY
A uni ed platform that fully meets
regulatory requirement
SOLUTION 4: In addition to chromatography, it also
IMPURITY covers a wide range of instruments SOLUTION 5:
IMPURITY
DETECTION including mass spectrometry, IDENTIFICATION
& PURITY spectroscopy, and balances
CONFIRMATION
Trap-free 2D LC/MS is a proven
Shimadzu PDA detector provides WORKFLOW platform for integrating
the unique deconvolution MANAGEMENT conventional LC and LC-MS/MS
function WITH LIMS Spend no more time on
Ensure that impurity peaks are LabSolutions provides an open data fractionation or development of
never missed interface to di erent vendors a separate method
Compatible with a wider range of LIMS
systems than other manufacturers
SOLUTION 8:
SOLUTION 6: QUANTITATIVE
CHIRAL DATA
SEPARATION SOLUTION 7: PROCESSING
DISSOLUTION
TESTING
SFC provides orthogonal LabSolutions provides new
chemistry for chiral separation algorithms on peak identi cation
Shimadzu's new LC connects online with and quanti cation
Likely to achieve better various dissolution testers
separation than normal phase Identify peaks in complex
chromatography One-step complete dissolution and matrices over a wider dynamic
analysis with automatic evaluation of range for accurate quantitation
results of both active ingredient and
impurities