Page 3 - LC-SFC_Pharma_Brochure
P. 3

Enhanced Pharmaceutical LC & SFC Workflows












                                                                                       SOLUTION 3:
              SOLUTION 1:                            SOLUTION 2:
                LC METHOD                               LC METHOD                           SAMPLE
              DEVELOPMENT                                TRANSFER                        PREPARATION
                                                                                        & PURIFICATION



          Method Scouting System automatically   New UHPLC/HPLC dual- ow LC              A range of con guration options for
          screens for the best combination of   system                                   preparative and puri cation
          mobile phases and column                                                       chromatography
                                                Easy implementation and one-click
          Minimize the time needed for method   transfer of chromatographic              Obtain higher compound purity and
          development without compromising      methods between di erent LC              faster puri cation e ciency than
          the quality                           instruments                              traditional methods




                                                DATA INTEGRITY

                                                 A uni ed platform that fully meets
                                                 regulatory requirement


             SOLUTION 4:                         In addition to chromatography, it also
                 IMPURITY                        covers a wide range of instruments             SOLUTION 5:
                                                                                                    IMPURITY
                DETECTION                        including mass spectrometry,                    IDENTIFICATION
                 & PURITY                        spectroscopy, and balances
              CONFIRMATION

                                                                                           Trap-free 2D LC/MS is a proven
           Shimadzu PDA detector provides       WORKFLOW                                   platform for integrating
           the unique deconvolution             MANAGEMENT                                 conventional LC and LC-MS/MS
           function                             WITH LIMS                                  Spend no more time on

           Ensure that impurity peaks are       LabSolutions provides an open data         fractionation or development of
           never missed                         interface to di erent vendors              a separate method

                                                Compatible with a wider range of LIMS
                                                systems than other manufacturers





                                                                                                SOLUTION 8:
             SOLUTION 6:                                                                         QUANTITATIVE
                 CHIRAL                                                                              DATA
              SEPARATION                               SOLUTION 7:                                PROCESSING
                                                        DISSOLUTION
                                                          TESTING
          SFC provides orthogonal                                                          LabSolutions provides new
          chemistry for chiral separation                                                  algorithms on peak identi cation
                                                Shimadzu's new LC connects online with     and quanti cation
          Likely to achieve better              various dissolution testers
          separation than normal phase                                                     Identify peaks in complex
          chromatography                        One-step complete dissolution and          matrices over a wider dynamic
                                                analysis with automatic evaluation of      range for accurate quantitation
                                                results                                    of both active ingredient and
                                                                                           impurities
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