Page 7 - LifeScience Solution for FNIRS

For Research Use Only. Not for use in diagnostic procedures.

Optical Brain-Function Imaging Light to Measure Brain Function Principle of Using Near Infrared

Features of Optical Brain-Function Imaging Data

Using near infrared light is safe, and the restraint level is low. Imaging Optical Brain-Function
It allows measuring brain activity status in a daily environment. Various Brain-Function Measurements Using the LABNIRS
Flexible adjustable curved surface holder (FLASH) can be used.
It allows fitting a wide range of head curvatures. It is suitable for both children and adults. (1) Simultaneous EEG and fMRI Measurement
Wide range of optional products available. By using the EEG simultaneous measurement holder (optional) and creating a system that bilitation Neuroreha-
Statistical processing software is included standard with systems, in addition to a wide assortment of optional products are comprises the LABNIRS and an EEG (Active Two system from BioSemi), a maximum of 133 fNIRS
available to help facilitate cutting-edge brain-function research, such as a simultaneous EEG measurement system, MRI fusion channels and 64 EEG channels can be measured simultaneously.
software, and a real-time data transfer function. Fibers can be extended (optional) for simultaneous fMRI measurements. Holder for simultaneous
Note: "FLASH" is an acronym for Flexible Adjustable Surface Holder EEG measurements
Patent No. 4254420
(2) Overlay with MRI Image
Higher Spatial and Temporal Resolution Overlaying the fNIRS data on an MRI image of the brain shape enables fNIRS and fMRI Comparison of
Accepts up to 40 sets––2.5 times more than before (142 channels max.). positioning the fNIRS functional image information more precisely.
Spatial resolution doubled with high-density measurements.
High temporal resolution (6 ms for 1 channel : previously 25 ms) sysytem captures raipid cerebral blood folow signals. -Work Flow-
25 ms 1. Import the DICOM image (TI-enhanced image) from the MRI (a).
2. Use the MRI fusion software to extract 3D scalp data (b). (a) (b) (c) Motor Control Brain Activity during
Conventional Sampling
3. Similarly, automatically extract the brain surface data to build
6 ms 3D brain surface data (c).
4. Entering the reference points (nasion cz, and left & right
New Sampling
Multi-Channel Measurements Normal Distribution High-Density Distribution preauricular points) and prove position (d). Measurement with EEG Simultaneous
5. Estimate the measurement position on the brain surface to
overlay the fNIRS data (e) to (g). (d)

LABNIRS Options Reference: Okamoto, M., H. Dan, et al. (2004) "Three-dimensional probabilistic
anatomical cranio-cerebral correlation via the international 10–20
system oriented for transcranial functional brain mapping." Analysis Method NIRS Signal
• MRI fusion software NeuroImage 21 (1): 99–111.
• Real-time data transfer software
• 3D position measurement system
• Video recording system
• Stimulus presentation system (e) (f) (g)
(3) Stimulus Presentation and Video Recording System
functional Near-Infrared Spectroscopy System for Research fNIRS measurements can be linked to a stimulus presentation system
LABNIRS Inner Speech Investigating
using a computer and video recording system.
*1
Holder: FLASH (Flexible Adjustable Surface Holder)
*1 Patented in Japan 04254420 Stimulus Presentation Video Recording
*2 Supports high-density, short-distance measurements System Subject System
Image Functions Language Processing
Speaker Mouse & Sound
keyboard
PC Record
Image
Response
Stimulus Operational
presentation monitor
monitor
Example of Brain Measurement Data
Forehead Fiber Holder Parietal Fiber Holder * 2 Temporal Fiber Holder * 2 Whole-head Fiber Holder Research Mental Disorder
during Imposed Task
Digital Video Data
Trigger Input References: Kohno, S., Ishikawa, A., et al. (2006)
Video Control "Application development of functional near-infrared imaging
system." Shimadzu Review 63 (3/4): 195–200.
Ishikawa, A., Kohno, S., et al. (2007).
"Application development of functional near-infrared imaging
system II." Shimadzu Review 64 (3/4): 177–183. Shimadzu fNIRS Key References Regarding
fNIRS System
EEG simultaneous Holder set for newborns Holder Kit
measurement Fiber Holder
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