Page 14 - Shimadzu Nexera UC - Nexera UC Prep

Purification

Compact, benchtop design System configuration examples

This space-saving benchtop model includes a carbon dioxide pump that does not require an external chiller (cooling system Stacked Fraction System: supports injection volumes up to 20 mL for large volume fractionation
for heat generated when pumping CO2 at high flow rates). In addition, one unit can handle a wide range of flow rates,
lowering installation costs.
This system is optimized for large volume
fractionation involving repeated injection of
samples which may contain several
compounds. The FRS-40 unit includes both
Benchtop system that can be installed anywhere injector and fraction collector functionality,
so that the same unit can be used for
Usually a chiller is required to cool the solvent delivery pump when pumping CO2 at high flow rates. However, the Nexera UC
repeated sample injections and gram-level
Prep features a compressor-type cooling unit, reducing the size of the system and allowing it to be installed anywhere. Its
preparative work. It supports injection
footprint is equivalent to an analytical scale SFC system.
volumes up to 20 mL* and collection of ten
fractions. Compatible with flow rates from
CO 10 to 150 mL/min and 10 to 30 mm I.D.
CO 2
Coolant line CO 2 560 mm 2
Pump
Pump Pump
columns.
Cooling *optional
Cooling
Footprint is unit
unit
reduced by
40% 1260 mm
1260 mm
Multi-Fraction System: for multiple peak fractionation of impurities and natural products
This system is suitable for preparative tasks
Chiller
Conventional preparative SFC system Nexera UC Prep involving samples with many peaks detected,
such as impurities in pharmaceutical
compounds. Volumes of up to 2 mL* can be
injected using an autosampler that holds up
Wide range of ow rates available to 162 samples (using 1.5 mL vials). Three
rack types can be selected for the FRC-40 SF
In a single system, the Nexera UC Prep can handle flow rates from 10 to 150 mL/min for fractionation of a range of sample sizes, fraction collector, which can recover up to
from a few hundred mg up to a few grams. Shimadzu provides various preparative systems, such as Nexera UC/s, which can 540 fractions (using 10 mL vials). With
perform SFC analysis and UHPLC analysis using a single system. The system corresponding to the application can be selected. support for flow rates from 10 to 150
mL/min, columns with an internal diameter
SFC from 10 to 30 mm can be used.
*optional

Nexera UC Nexera UC Prep

Analytical Fraction System: analytical ow and fraction collection in one system
0.1 mL/min 150 mL/min
Nexera UC/s 5IJT TZTUFN JT JOUFOEFE GPS BOBMZUJDBM TDBMF
GSBDUJPOBUJPO POMZ SFRVJSJOH GSBDUJPO WPMVNFT
PG TFWFSBM N- UP SFDPWFS VQ UP NH PG
NBUFSJBM VTFE UP DIFDL TZOUIFTJT GPS FYBNQMF
Nexera series Nexera Prep #Z DPOOFDUJOH BO '3$ 4' GSBDUJPO DPMMFDUPS
HPLC UP UIF /FYFSB 6$ TZTUFN BOBMZUJDBM DPMVNOT
GSPN UP NN * % DBO CF SVO BU GMPX SBUFT
VQ UP N- NJO GPS TNBMM WPMVNF GSBDUJPO
2.0 mm I.D. 4.6 mm I.D. 10 mm I.D. 20 mm I.D. 30 mm I.D.
DPMMFDUJPO

Approximate maximum 20 mg 500 mg 1 g
loading amount (single 100 mg
injection, 250 mm L. coulmn)

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