Page 5 - Shimadzu LCMS-8060

LCMS-8060

Triple Quadrupole Mass Spectrometer

Pushes the limits of what we can see

Fenoxaprop-ethyl Clofentezine Triclopyr
×10 6 ×10 5 1.5 ×10 5
Positive 7.5 Positive Negative
4.0 m/z 362.15>288.20 m/z 303.1>138.05 m/z 254.0>196.0
Sensitivity Speed Solutions LCMS-8060 5.0 LCMS-8060 1.0 LCMS-8060
S:×4.2
S:×3.3
S:×4.4
2.0
2.5 0.5
LCMS-8050 LCMS-8050
LCMS-8050
0.0 0.0 0.0
The LCMS-8060 is a ground breaking innovation in mass spectrometry helping to transform LC/MS/MS data quality by developing a new 10.0 10.5 11.0 min 9.5 10.0 10.5 min 5.5 6.0 6.5 min
vision of sensitivity and speed.
×10 4 ×10 4 ×10 3
1.0
2.5
Shimadzu is the first mass spectrometry company in the world to deliver a triple quadrupole mass spectrometer with the highest 1.0 0.5
sensitivity and ultra-fast technologies to create an innovation that really matters. 0.0 0.0 0.0
10.0 10.5 11.0 min 9.5 10.0 10.5 min 5.5 6.0 6.5 min
MRM chromatograms: 100 ng/mL neat standard, upper: signal comparison, lower: baseline noise comparison
By redefining the ion focusing capability on the UF-Qarray , the LCMS-8060 brings a
™
Sensitivity meaningful impact to quantitative detection and opens new opportunities for scientists to
deliver solutions that make a true difference. Built on the proven platform of the LCMS-8050, the new patented sensitivity compared to previous technologies. The chromatogram
ion guides developed for the LCMS-8060 greatly improves ion for each pesticide has been magnified to show the noise has not
The newly developed UF-Qarray ion guide is a groundbreaking technology that increases production and collisional focusing without affecting noise. increased with a higher ion production. Innovations in ion guide
LC/MS/MS sensitivity by enhancing ion signal intensity and reducing noise. By improving The ion production, transmission and detection of three pesticides technologies not only delivers new limits of MRM sensitivity but
the ion sampling device, the ion guide, and the vacuum efficiency, the LCMS-8060 delivers (fenoxaprop-ethyl, clofentezine and triclopyr) results in increased has an impact on full-scan sensitivity.
a new vision of sensitivity and makes a real difference to working better and faster.
Heated ESI
Probe

Inten. (×10,000)
LCMS-8060

8.5–12.5 min 3.00 520.4 LCMS-8050
Drying Gas 2.50
LCMS-8060
2.00
1.50
1.00
Heating Gas 1.5 × 10 7 0.50
DL (Desolvation Line) 0.00
3.00
UF-Qarray UF-Lens ™ 2.50
LCMS-8050
2.00
1.0 × 10 7
1.50
1.00
0.50 520.5
0.5 × 10 7 0.00
500 750 m/z
0
8.0 9.0 10.0 11.0 12.0 13.0 14.0 15.0 16.0 17.0 18.0 min
Comparison between the LCMS-8060 (purple) and LCMS-8050 (blue) for the analysis of lipids
(precursor ion scanning at m/z 184-choline-containing phospholipids in positive ion mode)

Lipid profiling on the LCMS-8060 can detect more ion signals with LCMS-8060 systems using a scan speed of 3,000 u/sec. With the
greater precision and with higher confidence. After protein LCMS-8060 lower levels of phosphatidylcholine could be detected
precipitation, the human serum sample was diluted 1000 times by in a human serum sample following a protein crash sample
methanol and 1µL was injected onto the LCMS-8050 and preparation compared to the LCMS-8050.

4 Liquid Chromatograph Mass Spectrometer LCMS-8060 5