Page 6 - Shimadzu LCMS-8040
P. 6

Proven Ultra-High Performance now

            with Enhanced Sensitivity


                Higher Sensitivity for Q1 Full Scan Spectra

            The LCMS-8040 maintains the same high-speed scanning (UFscanning) and polarity switching
            technology (UFswitching) utilized in the LCMS-8030.

            The LCMS-8040 not only maintains Shimadzu's proprietary   pesticide samples (Methomyl, Carbaryl(NAC), Phoxim, Benfuracarb,
            high-speed technologies (UF Technologies, USP7855355, USP8188426),   and Abamectin B1a) is shown below. The upper spectra were
            which minimize sensitivity losses even at faster scan speeds, it also   acquired using the LCMS-8040 and the lower spectra were acquired
            features improved ion optics, which provide higher sensitivity for   using the LCMS-8030. As shown, the LCMS-8040 offers significant
            MRMs and full scans. A comparison of Q1 full scan spectra for   sensitivity improvements for precursor ions or full scan data.
                    LCMS-8040
                    Inten.(×10,000,000)            Inten.(×10,000,000)             Inten.(×10,000,000)
                  2.0                            2.0                            2.0
                              ×4                   ×2          ×3                             ×3
                    ×2                                                             ×2
                  1.5                            1.5                            1.5
                      ×3                             ×3                              ×3
                  1.0     ×3                     1.0     ×3                     1.0     ×3
                                                                       ×5                              ×5
                  0.5                   ×5       0.5                            0.5
                     200  300  400  500  600  m/z   200  300  400  500  600  m/z    200  300  400  500  600  m/z
                             15000 u/sec                    10000 u/sec                     5000 u/sec
                    LCMS-8030
                    Inten.(×10,000,000)            Inten.(×10,000,000)             Inten.(×10,000,000)


                  2.0                            2.0                            2.0
                  1.5                            1.5                            1.5
                  1.0                            1.0                            1.0
                  0.5                            0.5                            0.5

                     200  300  400  500  600  m/z   200  300  400  500  600  m/z    200  300  400  500  600  m/z
                             15000 u/sec                    10000 u/sec                     5000 u/sec


                Proven Interface for Robust Performance

            Robust, User-Friendly Interface
            The LCMS-8030 and LCMS-8040 use the same interface. In LCMS
            analysis, it is necessary to adjust interface conditions such as
            temperatures and gas flow rates for optimal desolvation. Spray
            needle adjustment and probe position are also factors to be
                                                                   Central position  −2 mm  +3 mm  Integrated
            evaluated. In both the LCMS-8030 and LCMS-8040, temperatures
            and flows are easily controlled through the software. ESI probe   Locking screw        ESI Capillary
            position is set by a single easily accessible knob, and spray needle   Position
                                                                  adjustment knob
            protrusion is adjusted without the need for any special tools or
            disassembly of the probe. In addition, this capillary incorporates a
            tapered design, which reduces sample clogging.                Attach/detach with
                                                                          a single flip of a lever
















      6                 Sp e e d  B eyond  C o mp ari s on  E n h a nc e d  Se n s itivit y
   1   2   3   4   5   6   7   8   9   10   11