Page 9 - Shimadzu iMScope QT

Effortless Performance for Accurate Mass

Excellence in Mass Measurement Accuracy (MMA)

Mass measurement accuracy (MMA) is the key performance
attribute underlying all application elds using high-resolution
accurate-mass (HRAM) spectrometers. The LCMS-9030 delivers
the MMA needed for high-con dence identi cation of
unknown compounds at an unprecedented level of stability.
This is made possible by new technologies implemented in
the Intelligent Temperature Control System and the
UF-FlightTube that accurately offset the changes occurring to
both internal and external environments. With the LCMS-9030,
Shimadzu aims to totally refashion the HRAM user experience,
enabling scientists to run more samples at longer calibration
intervals with greater con dence and ease.

Intelligent Temperature Control System (Patent pending)

Stable MMA Against Temperature Fluctuation

Shimadzu’s Intelligent Temperature Control System ensures Without additional mass correction, the measured accurate
stable MMA even in laboratory environments susceptible to masses of all compounds remained within 1 ppm of the
temperature changes. To demonstrate, standards ranging theoretical mass for the 60-hour duration of the experiment.
from 150 to 1700 Da were analyzed continuously after a With the LCMS-9030, laboratory productivity can be
single calibration. Normal laboratory temperature uctuation increased by running long, calibration-free batches with
was observed between 25°C and 28°C. con dence.

Positive Mode Negative Mode

3 2 29 3 2 29

27
27
Deviation from true mass m/m [ppm] −1 1 0 25 Temperature [°C] Deviation from true mass m/m [ppm] −1 1 0 25 Temperature [°C]

23
23
21
21
19
19
−2

15
−3
−3 17 −2 17
15
0 12 24 36 48 60 0 12 24 36 48 60
Time after calibration [hr] Time after calibration [hr]
Acetoaminophen Anisomycin Doxorubicin Salinomycin
Progesterone Mitomycin C Thiostrepton Tubercidin
Griseofulvin Doxorubicin Valinomycin Mitomycin C
Rifampicin Valinomycin Temperature
Temperature

iMScope QT
Imaging Mass Microscope 9