Page 4 - Shimadzu Co-Sense Series
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Co-Sense for BA
Basic Concept of Co-Sense for BA
The Co-Sense for BA automatically and seamlessly performs all processes from sample pretreatment to analysis. This is achieved using
a column-switching HPLC system equipped with the innovative Shimadzu Shim-pack MAYI-ODS pretreatment column and a unique
on-line dilution bypass channel design.
Trapping and Concentration
The dilution pump is used to dissociate large and small molecules to increase recovery of target analytes. This has the effect of
breaking up large and small molecule complexes. This automatic dilution process ensures reliable trapping and concentration of
target components by suppressing their interactions with the matrix and the impact of the sample solvent.
Pump unit for analysis
Analysis column Detector
Trap column
Pump unit for
on-line dilution
Pump unit for
sample injection
Autosampler
Analysis
Once unwanted constituents have passed through the trapping column to waste, the target compounds are removed by a second
independent gradient. Valve switching is used to transfer the target compounds through the second dimension column for analysis
detection.
Pump unit for analysis
Analysis column Detector
Trap column
Pump unit for
on-line dilution
Pump unit for
sample injection
Autosampler
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