Page 83 - Application Handbook - Liquid Chromatography

4. Pharmaceutical

Progress in medical and pharmaceutical technology is a key Shimadzu’s systems cover applications in
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driver to increase people’s life expectancy. Furthermore, • ife science research for pharmaceuticals
research leading to advanced diagnostics, treatments and (genomics, proteomics, metabolomics, glycomics)
therapies assists in fighting and curing illnesses. Drugs help to • drug discovery (biomarker discovery, screening and
overcome diseases or in case of chronic or incurable disorders, drug synthesis)
they support being able to continuously take part in social life. • drug development (pre-clinical development, toxicology,
pharmacology, formulation, process development)
Side effects from interfering substances and contaminations • drug metabolism (ADME, DMPK)
in drugs are undesirable. This is why it is important to use • manufacturing and QA/QC (process for production,
the purest possible substances and purified equipment and quality control and assurance)
materials in the production of drugs. In pharmaceutical pro- • biopharmaceutical (protein characterization, impurity
duction, methods and rules for the manufacture, storage, analysis for quality assurance)
quality and testing of drugs are standardized and defined in • herbal medicine/natural products
Pharmacopoeias. • material testing (bending tests, crushing strength,
dissolution time, compression tests).
From Drug Discovery to Quality Control, Shimadzu’s wide
range of solutions supports the pharmaceutical industry
through chromatography (HPLC, SFC and GC), spectroscopy
(UV-VIS, FTIR, AAS, ICP), mass spectrometry (LC-MS, GC-MS),
sum parameter (TOC) and MALDI-TOF systems, including MS
imaging. Shimadzu combines a long history in the market with
a comprehensive product portfolio and expertise in regulatory
compliance, making the company the perfect partner for the
pharmaceutical industry. Find more information on: www.shimadzu.eu/pharmaceutical