Page 51 - Pharmaceutical Solution for Pharma Analysis

Application No. G290
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„ Class2
Due to the large number of components in the Class 2 the Class 2 standard solution Mixture A chromatogram
standard solution, it was separated into two mixtures: be 1.0 or greater.
A and B. Respective measurement results are shown in Fig.3 shows that, using the Restek SH-Rxi-624SilMS
Fig.3 and Fig.4. Procedure A requires that the low-bleed column, the specified peaks are completely
resolution for acetonitrile and methylene chloride in
separated, with a resolution of 2.4.
11 12 13 14
1: Methanol
3 4 5 6 7 8 15
2: Acetonitrile
3: Methylene chloride (DCM)
4: trans-1,2-Dichloroethylene
5: cis-1,2- Dichloroethylene
6: Tetrahydrofuran
7: Cyclohexane
8: Methylcyclohexane
1 9: 1,4-Dioxane
10: Toluene
11: Chlorobenzene
2
12: Ethylbenzene
13: m,p-Xylene
9 14: o-Xylene
15: Cumene
0 2.5 5.0 7.5 10.0 12.5 15.0 17.5 20.0 22.5 25.0 27.5 30.0 32.5 min

3 4
Resolution 2.4
1
2

2.0 3.0 4.0 5.0 6.0 min

Chromatogram of WATER-SOLUBLE ARTICLES Class 2A Standard Solution by Procedure A

1 5 8
7
1: Hexane
2: Nitromethane
3: Chloroform
4: 1,2-Dimethoxyethane
5: Trichloroethene
6: Pyridine
7: Methylbutylketone
3 8: Tetraline
6

2
4

5.0 10.0 15.0 20.0 25.0 30.0 35.0 min

Chromatogram of WATER-SOLUBLE ARTICLES Class 2B Standard Solution by Procedure A

First Edition: Jun. 2017
For Research Use Only. Not for use in diagnostic procedure.
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