Page 76 - Clinical-Medical Solution for Clinical Chemistry

Quantitative Multi Target Screening (MTS) using liquid
chromatography-tandem mass spectrometry with MS/MS library
based identi cation for forensic toxicology

Conclusions

A spectral based library of more than 1200 compounds clinical and forensic toxicology was successfully applied to
has been created using certi ed reference materials whole blood samples spiked with a panel of compounds.
acquired at three collision energies on a triple quadrupole All compounds were detected at highest concentration
mass spectrometry platform. and positively identi ed using product ion scan MS/MS
A MRM triggered product ion spectra method to quantify library based searching generating higher data quality for
and identify a panel of compounds commonly found in compound identi cation.

Disclaimer: The Shimadzu LCMS-8060 is intended for Research Use Only (RUO). Not for use in diagnostic
procedures.

First Edition: June, 2016
For Research Use Only. Not for use in diagnostic procedure.
This publication may contain references to products that are not available in your country. Please contact us to check the availability of these
products in your country.

The content of this publication shall not be reproduced, altered or sold for any commercial purpose without the written approval of Shimadzu.
Company names, product/service names and logos used in this publication are trademarks and trade names of Shimadzu Corporation or its
affiliates, whether or not they are used with trademark symbol “TM” or “®”. Third-party trademarks and trade names may be used in this
publication to refer to either the entities or their products/services. Shimadzu disclaims any proprietary interest in trademarks and trade names
www.shimadzu.com/an/ other than its own.
The information contained herein is provided to you "as is" without warranty of any kind including without limitation warranties as to its
accuracy or completeness. Shimadzu does not assume any responsibility or liability for any damage, whether direct or indirect, relating to the
use of this publication. This publication is based upon the information available to Shimadzu on or before the date of publication, and subject
to change without notice.
© Shimadzu Corporation, 2016