Page 7 - Shimadzu GCMS-TQ8050 NX

Reliable Operation
Accurate Processes from Method Creation to Data Analysis

The Smart Database series, which are specialized for various fields, and Smart MRM function, which optimizes sensitivity, can be used 4NBSU .3.
to accurately create methods for ultra-trace analysis and reliably achieve high-sensitivity analysis from MRM measurements. The
LabSolutions Insight software, designed to support quantitative analysis of multianalyte data, enhances the throughput of data Automatic Method Creation
analysis from simultaneous analysis of multiple components in trace concentrations. The extensive accuracy control functions enable
decisions to be made based on the easy-to-understand visualization of quantitative analysis and accuracy control results. The Smart MRM technology automatically creates methods with measurement times optimized for each component based on the Smart
database. The Automatic Adjustment of Retention Time (AART) function incorporated in the system estimates retention times with high
accuracy. When creating methods for simultaneous multicomponent analysis, the complicated process of configuring measurement parameters
.3. 0QUJNJ[BUJPO 5PPM made it difficult to prepare appropriate methods. By using the Smart MRM function, however, it is possible to automatically create methods in
which data are acquired with high sensitivity only during the elution time of the target components. In addition to MRM methods, SIM
Optimize MRM Transitions Automatically methods can be created.
Determining and optimizing MRM transitions for new compounds can require significant development time. The “MRM Optimization Tool“
automates the process by collecting product ion scan data and finding the optimum collision energy for each transition.
Once established, the transitions are registered to one of the Shimadzu “Smart Database” files, and the MRM or Scan/MRM methods are
created using Smart MRM.

Dichlorvos Fenobucarb
1.200 1.200
1.000 1.000
0.800 0.800
109.00 > 79.00 121.00 > 77.10
0.600 0.600 Parameter Setting
185.00 > 93.00 150.00 > 121.10
185.00 > 109.00 121.00 > 103.10
0.400 0.400
Automatic Adjustment of
Compound Retention Time (AART)
0.200 0.200
(Automatic Adjustment of Retention Time)
0.000 0.000
3 6 9 12 15 18 21 24 27 30 33 36 39 42 45 3 6 9 12 15 18 21 24 27 30 33 36 39 42 45
C17 C18 C19
Originally registered
method information
4NBSU %BUBCBTF 1700 1735 1800 Retention index
C17 C18 C19
Customer's Identification
Method Management Achieved by Database File instrument window
The Shimadzu “Smart Database” is a database file for creating the method files using “Smart MRM” function. In addition to compound 1700 1735 1800 Retention index
information and transitions, retention index can be registered in the database file. Method creation can be proceeded without calculating the
21
22
retention time by analyzing the standard samples when using the Automatic Adjustment Retention Time (AART) function. In addition to MRM 20 21.1 min 21.5 min Retention time
(Originally registered RT)
information, Scan and SIM ion information, mass spectra and calibration curve information from the internal standard method can also be (Calculated RT) Automatic adjustment Analyte
registered in the database file. This allows users to create their own database easily. Automatic Estimation Dwell Time Optimization
of Retention Times
The AART function adjusts the retention times of target components
based on linear retention indices (LRI) and the retention times of
n-alkanes. The AART function easily adjusts acquisition and
processing method parameters simultaneously.

Automatic Creation
of Analysis Methods

12 Gas Chromatograph Mass Spectrometer 13