Page 58 - Pharmaceutical- Guide to Biopharmaceutical

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TORAST-H Series

Shimadzu original low adsorption glass vial Shimadzu original low adsorption

TORAST-H Glass Vial polypropylene vial Cell Line Optimization
TORAST-H Bio Vial

benefits benefits Culture

• Low adsorption glass vial suitable for long-term storage. • Extremely low adsorption of peptides
• Minimized adsorption of bases, acids and neutrals • Extremely low adsorption of basic compounds
• Superior quality control • User-friendly design

Adsorption Test for Long-term Storage Adsorption Test Using Trypsin Digestion Products of Myoglobin (approx. 1.9 pmol/mL) Purification
When a sample is stored in a general vial for a long time, the sample may adsorb into the surface of the vial, causing the reproducibility to be poor. The results confirmed the phenomenon that highly polar peptides with retention times detected between approx. 7 and 8 minutes mostly adsorb to glass
The TORAST-H Glass Vial contains low adsorption characteristics that makes it excellent for long-term sample storage. vials, whereas highly hydrophobic peptides with retention times detected between approx. 12 and 16 minutes mostly adsorb to polypropylene (PP) vials.

TORAST-H Bio vials Glass vials Polypropylene (PP) vials
Basic Compounds A (log P 4.5, pKa 10.5) Adsorption especially
Adsorption to glass vials
to PP and glass vials Characterization

Recovery (%) Glass Vial A Glass Vial A

Glass Vial B
Glass Vial C
Glass Vial B
Glass Vial C Quality Control

Note: The area at time 0 of the PP vial (Controls) was set at 100 %.
After 3 months, the recovery rate of PP vials was 89 %, which was lower than that of TORAST-H Glass Vial. Exterior Design that Enables Using Vials Directly for Flash Centrifugation
Centrifuge

Product Details Cap Slit Volume Qty. P/N
Droplets
Clear glass with a label No 370-04300-01 Sample loss
(wide diameter 9-425) Yes 370-04300-02 Pharmacokinetics
1.5 mL
Amber glass with a label No 370-04300-03 Air entrainment
TORAST-H Glass Vial (wide diameter 9-425) Yes 370-04300-04 Prevents specified injection
(Includes the quality certificate
and PTFE/Silicone septum) Clear glass with a label Screw, Black No 100 370-04301-01
(wide diameter 9-425) Yes 370-04301-02
150 µL Product Details Slit Volume Qty. P/N
Amber glass with a label No 370-04301-03
(wide diameter 9-425) Yes 370-04301-04 TORAST-H Bio Vial PP vial Yes 300 µL 100 370-04350-00 Others
Screw Cap for PTFE/Silicone septum No 370-04310-01 If using a Shimadzu i-Series LC system, use the special vial detection plate (P/N: 228-51891-03) shown to the right.
TORAST-H Glass Vial (wide diameter 9-425) Yes － 370-04310-02

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