Page 11 - Shimadzu LCMS-8050

UFscanning

UFsensitivity

UFswitching
UF-MRM

Maintain Sensitivity and Mass Accuracy Inten. (×1,000,000)
Even at 30,000 u/sec 1.0 115.9 5,000 u/sec
Greater ion transmission at any scan speed has been achieved by precisely controlling 642.2
0.5
the voltage applied to the quadrupoles across the mass scale. As Shimadzu quadrupole
202.9 370.2 555.2
technology using a data collection interval of 0.1 u high quality mass spectra are 70.1
acquired without loss of sensitivity or mass accuracy. 0.0
250 500 m/z
Inten. (×1,000,000)
10,000 u/sec
1.0 115.9
1 u steps
0.5 642.2
-2 -1 True value +1 +2 m/z Top of peak is not defined 202.9 370.2 555.3
resulting in a large variation 70.0
in the m/z determination. 0.0
250 500 m/z
0.5 u steps Inten. (×1,000,000)
-2 -1 True value +1 +2 m/z 30,000 u/sec
1.0
115.9
Proper data collection
rate allows accurate 0.5 642.1
0.1 u steps determination of m/z value. 202.7 370.2 555.2
70.1
0.0
-2 -1 True value +1 +2 m/z 250 500 m/z
Variation in m/z Caused by Different Sampling Intervals for Spectral Data Bradykinin (MW 756.4) Product Ion Scan Spectrum
Precursor Ion m/z 379.4

Efficient Qualitative Analysis Using Synchronized Survey Scan ™

The Synchronized Survey Scan (SSS) function allows MRM acquisition to be combined with other scan modes including library searchable spectra using
a MRM triggered product ion scan.

One thousand events can be registered
within a single method supporting the
analysis of large panels of target
compounds with high data quality and
greater information.

An Example Method for Performing an MRM-Triggered Product Ion Scan

Liquid Chromatograph Mass Spectrometer /&06 11