Page 9 - Shimadzu SALD-2300

By enabling measurement under wide particle Changes in particle size distribution can be monitored in real-time.
High sensitivity / High concentration concentration conditions (0.1ppm to 20%), changes High speed Continuous measurement function at 1-second intervals can record these processes
in particle size distribution depending on particle for additional analysis.
concentration can be evaluated.
Particle size distribution data and light intensity distribution data can be displayed in real-time.
Previously, the particle concentration of a sample had to be adjusted to meet the optimum conditions of analyzers by dilution or concentration using This means that sample changes over time or shifts in the dispersion status can be monitored in real-time.
a centrifuge. In these cases, changes in particle size distribution, such as agglomerations or dispersions, could not be considered. Since both the light intensity distribution data, which is the raw data, and particle size data can be monitored simultaneously, they can be
compared to keep track of any changes in the status of samples.
Dispersions and agglomeration can be caused by dilutions.
In some cases, dilutions can accelerate dispersions, but in other cases, they can create agglomerates. Continuous measurement can record a maximum of 200 data sets at minimum 1-second intervals.
To ensure optimum, the initial particle concentration must be determined without dilutions or concentrations. Maximum 200 particle size distributions at minimum 1-second intervals can be measured and stored continuously. These data can be
After the evaluation of particle size distribution at the initial state, the effects of particle concentration from dispersions and analyzed from various angles using statistical processing, time series analysis and 3-dimensional graph functions.
agglomerations must be evaluated.
Statistical processing
Wide particle concentration range must be covered to evaluate the dissolution process of sample particles.
This is necessary because the progress of dissolution makes the particle concentration low in comparison to the first particle concentration.

SALD-2300 can measure particle size distribution under the conditions of particle concentration from 0.1ppm to 20%.
When the sampler SALD-MS23 or batch cell SALD-BC23 is used, measurements are possible under conditions of concentration from 0.1ppm to
100ppm.
When the high-concentration sample measurement system SALD-HC23S is used, high-concentration samples up to 20% can be measured Updates particle size distributions Time series analysis
because the negative effects of multiple scattering are prevented. and light intensity in real time

q3(%)
30 30 Measurement without dilution of hand cream
In the case of hand cream, dilutions make the particle size
Normalized Particle Amount (Diff) 20 20 distribution narrow. Particle size distribution / Light intensity distribution 3-dimensional graph
25
25
Measurements without dilutions must be done to obtain
15
15
accurate measurement.
Simultaneous and real-time display
10
10
5
5
Cross reference of particle size distribution and light intensity distribution enables multilateral evaluations of dissolution process.
0 0
0.01 0.05 0.1 0.5 1 5 10 50 100 500 1000 5000 (%)100% = 60000 q3(%)
Particle Diameter (µm) 100 10 10
q3(%)
Q3(%) 80 8 8
100 20 Evaluation of a fine particle included in red wine Light Intensity 60 Normalized Particle Amount (Diff) 6 6
Normalized Particle Amount (Cum) 60 15 Normalized Particle Amount (Diff) the state of the undiluted solution. 40 20 0 10 20 Sensor Element Number 50 60 68 72 4 2 0 0.1 0.5 1 Particle Diameter (µm) 5 10 50 4 2 0
The graph to the left shows the result of measuring red wine in
80
The low-concentration sample can be measured as an undiluted
10
solution.
40
40
30
Measuring it in this state can remove the influence of dispersion
20
shows how dissolution progresses from smaller diameter particles and how the normalized amount of large particles increases.
0 5 0 or agglomeration by the concentration operation. This is an example of light intensity distribution data and particle size distribution data for the dissolution process of calcium carbonate. It
0.01 0.05 0.1 0.5 1 5 10 50 100 500 1000 5000
Particle Diameter (µm)
q3(%) q3(%)
30 30
Evaluation of negative electrode material of a 20 15 20 15
secondary battery
25
Normalized Particle Amount (Diff) 20 20 At left is a graph showing the results of measuring a carbon Normalized Particle Amount (Diff) 10 5 10 5 Normalized Particle Amount q3(%) 2 1 Particle Diameter (µm) 500 1000 5000
25
20
black particle.
16
12
15
15
8
100
The agglomeration particle (micrometer range) has been
50
4
10
0
10
10
5
dispersed to the fine particle (sub-micrometer range) by
1
4
5
5
5
0
dispersion processing using a homogenizer. The sample (sample
0.5
0.05 0.1
0.01
10
5
1
Particle Diameter (µm) 50 100 500 1000 5000 0 3 File No. 6 7 8 9 0.01 0.05 0.1 0.5
0 0 that absorbs light like the carbon black) that doesn't transmit 10
0.01 0.05 0.1 0.5 1 5 10 50 100 500 1000 5000
light easily can be measured based on the improvement in
Particle Diameter (µm) This is a result of measuring the process by which a powdery digestive medicine is distributed into water.
The particle size distribution can be displayed by the 3D graph. In a 3D graph, the dispersion process that changes from the large particle to the
sensitivity.
small particle is easily viewed.
SALD-2300
8 Laser Diffraction Particle Size Analyzer 9