Page 5 - Shimadzu LCMS-2020

Speed is Power.

Accurate mass analysis of sharp chromatographic peaks obtained by UFLC requires ultra-fast MS detection capabilities.
Greater speed. The LCMS-2020 offers UFswitching for rapid polarity switching between the positive and negative ionization modes
and UFscanning for ultra-fast scan measurements to capture the sharpest UFLC peaks.
Greater sensitivity.

Ionization Probe

Desolvation Line Entrance Lens

Skimmer Pre-rod Main-rod Detector
reservoir pump auto column detector
sampler oven

Enhances sensitivity by
From HPLC to UFLC preventing ion divergence
UFLC achieves excellent speed and resolution, while offering the Octopole
high precision not available with conventional HPLC and Ion Source Qarray Quadrupole
expandability options.

mAU
400 Ultra-fast Ultra-fast Ultra-fast
UFswitching UFsensitivity UFscanning
300
Rapid 15-millisecond positive/negative ionization switching Superior sensitivity from UFLC 15,000 u/sec scan speed
200 ®
To detect both positive and negative ions, analysis is performed while switching Newly developed Qarray Optics achieve superior Shimadzu's proprietary scanning technology (Patent:
between the positive and negative ionization modes. sensitivity, reproducibility, and linearity. US8188426) maintains resolution and achieves high
100
The LCMS-2020 adopts patented high-voltage power supply technology (Patent: ion transmission even at high scanning speeds.
US7855355) to achieve an ultra-fast polarity switching time of just 15 ms. 1pg Reserpine on column ESI
0 (×1,000)
0.00 0.25 0.50 min. m/z 609.3 Area %RSD: 2.06% (n = 6)
Polarity switching time Polarity switching time 9.50 S/N (RMS)
15 msec 15 msec 356.3 355.7 351 345 341.3 351
Ultra Fast Positive-ion Negative-ion Positive-ion 9.25
measurement
measurement
measurement
SIM 2CH SIM 2CH SIM 2CH 9.00
Not only high-speed analysis, but
increased overall speed through rapid (×100,000) 8.75 (×1,000,000) 414
sample injection and fully automatic 8.0 −: 321 1.5 256
7.5 +: 344 8.50 1.4 267
analysis functions.
7.0 −: 329 1.3 278
+: 231 8.25
6.5 1.2
Unquestionable Fidelity 6.0 10.0 15.0 20.0 25.0 30.0 35.0 40.0 45.0 min 1.1
UFLC offers exceptional injection 5.5 1.0
reproducibility as well as ultra 5.0 Calibration curve: 0.1, 1, 10, 100, 1000 pg 0.9
4.5 8E6
high-speed operation. 0.8
4.0 7E6
In terms of minimizing sample 3.5 0.7
carryover, essential in LC/MS analysis, 3.0 6E6 pg Area 0.6
5E6 0.5
the LCMS-2020 stays ahead of the 2.5 Area 4E6 0.1 802.5 0.4
competition. 2.0 1 7743.5 0.3
1.5 3E6 10 84799.7 0.2
1.0 m/z 321: Chloramphenicol 2E6 100 891423.7 m/z 414: L-α-Narcotine
Ultra Flexible 0.5 m/z 344: Dibucaine 1E6 1000 7864342.1 0.1 m/z 256: Diphenhydramine
m/z 329: Furosemide
m/z 267: Desipramine
Covers an extensive range from 0.0 m/z 231: Isopropylantipyline 0 0.0 m/z 278: Amitriptyline
0 200 400 600 800 1000 0.00 0.25 0.50 0.75 min
ultra-fast analysis to conventional HPLC 0.00 0.25 0.50 0.75 min Conc. [pg]
and semi-preparative analysis.
LCMS-2020
4 Liquid Chromatograph Mass Spectrometer 5