Page 9 - Shimadzu HS-20 NX series

Beyond Expectation

Ultra-sensitive analysis Analysis of extractables and leachables contained in packages

It has been pointed out that there are
safety concerns about extractables and
Trace Fragrance Analysis in Spices leachables contained in pharmaceutical
by HS-20 NX Trap Mode packages and medical devices leaching
5 6 7 8 9
1
into human bodies and medicines. Thus, it
3 10 In some cases, the HS-20 NX loop model may is required to understand residual solvents
4
11 not be sensitive enough to analyze trace and residual monomers contained in
amounts of flavor in food samples like spices. polymers. The use of the HS-20 NX trap
2
3 Trap
The HS-20 NX trap model can concentrate the mode and the Xtra Low Bleed HS septa,
Loop TD-30
analytes in a sample by using some trap which is made of highly heat resistant and
5.0 7.5 10.0 12.5 15.0 17.5 materials, which enables ultra-sensitive clean material, enables the analysis and HS-20 NX
Trap
analysis. evaluation of extractables and leachables, HS-20 NX
1 Acetic Acid 4 beta. - Pinene 7 gamma. - Terpinene 10 Cuminaldehyde
Loop
2 2,3-Butanediol 5 D-Limonene 8 Linalool 11 Geranyl acetate
an analysis that is difficult with the loop
3 alpha - Pinene 6 m-Cymene 9 Camphor 2.5 5.0 7.5 10.0 12.5 15.0 17.5 20.0 22.5
mode.
Comparative Analysis of Extracts from Eye Drops Caps
(TD-30 vs HS-20 NX Trap mode vs HS-20 NX Loop mode)

Sample enrichment using an electronic cooling trap

The HS-20 NX Trap model includes an electronic cooling trap. Since the HS-20 NX Trap models can be cooled down to
-20 °C or less, it is possible to concentrate and analyze chemicals over a wide boiling range.

Area 4.5
4.0 Ethylene
3.5 Ethane
3.0 Propane
2.5
loop model Ethylene (B.P. -103.7 C) Ethane (B.P. -89 C)
2.0
1.5
1.0
0.5
0.0
1 Trap 2 Trap 3 Trap 5 Trap
With the trap mode of the HS-20 trap model,
which can concentrate samples, 10 - 100 times
5 Trap Trap Ethylene Ethane Propane
more sensitive analysis can be achieved than X1 1.0 1.0 1.0
Loop
with the loop mode. The HS-20 trap model X2 2.1 2.0 2.0
also operates in the loop mode, giving users X3 2.6 2.6 2.7
X5 4.0 3.7 3.8
the flexibility to meet multiple analytical 1.75 2.00 2.25 2.5 2.75 3.00 3.25 3.5 3.75 4.0 4.25
trap model requirements. Comparison of analysis of 1 ppm of hydrocarbons (loop vs trap x 5)

8 9