Page 4 - Shimadzu Solutions for Food Safety & Halal Testing

Enhancing Capabilities in Pesticides Analysis

Using the Shimadzu Extended MRM Pesticide Library (the Library
includes information on 750 certified reference materials) a
single multi-residue LC/MS/MS method was developed for
646 pesticides (3 MRM transitions for each targeted pesticide
resulting in 1,926 ransitions in total, with a polarity switching
time of 5msecs) using the state-of-the-art LCMS-8050 and
LCMS-8060.

2000000
646
647 pesticides in 10.5 minutes
3 MRMs per compound (1,929 transitions)
1,926
5ms rapid positive/negative switching
1750000
1500000
1250000

1000000

750000

500000

250000

0
0.0 1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0 9.0 10.0 min
646
Figure 1. Chromatogramof647 pesticides spiked into amintextract at 0.010mg/kg (3 MRMs percompoundand 5ms polarity
switchingtime).

Analysis of more than 400 pesticides that used to require two
or three methods can now be accomplished with Shimadzu
high performance TQ-8040 GCMS/MS in a single acquisition
method created by Smart MRM function, significantly increasing
laboratory throughput.

Shield Temperature
LowH igh
: Filament
: Electric field
: Heat rays

7.0
Shield 6.0
5.0
4.0
3.0
2.0
1.0
5.0 7.5 10.0 12.5 15.0 17.5 20.0 22.5
Simultaneous Analysis of 439 Pesticides Using UFMS and Smart MRM
8.0 278.00>109.00 3.0 165.10>108.10 2.5 314.00>245.00 264.00>176.00
7.0 278.00>125.00 2.5 165.10>93.00 314.00>56.00 7.5 264.00>232.00
6.0 278.00>169.00 165.10>65.00 2.0 314.00>271.00 264.00>148.00
Smart Database 5.0 2.0 1.5
4.0 1.5 5.0
3.0 1.0 1.0
2.0 2.5
MRM Optimization Tool 1.0 0.5 0.5
12.75 13.00 13.25 13.50 16.75 17.00 17.25 17.50 17.00 17.25 17.50 17.75 21.25 21.50 21.75 22.00
Fenthion %RSD = 4.16% Pyributicarb %RSD = 2.39% I prodione %RSD = 4.54% I ndoxacarb %RSD = 4.03%
Mass chromatogram and %RSD (5 ppb)
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