Page 17 - Clinical-MedicalSolution for Medical Chemistry

HPLC/SFC Column Guide

Shim-pack Scepter HPLC Columns Shim-pack UC SFC Columns

Excellent stability and performance could be achieved under a wide range of LC conditions with Shim-pack Shim-pack UC series columns are designed speci cally for Nexera UC series SFC systems. When using
Scepter LC columns, which are the next generation organic silica hybrid based columns. With different supercritical uids for analysis, separation behavior can vary signi cantly depending on the type of solid
chemistry characteristics, Shim-pack Scepter columns are effective for method development/scouting with phase. To optimize separation, a variety of columns should be used to determine the parameter settings. The
suitability for use in a wide variety of applications. With different particle sizes (1.9 m, 3 m, 5 m) and extensive choice of column sizes available means that operations can be scaled up seamlessly from analytical
different column dimensions, Shim-pack Scepter LC columns are fully scalable between UHPLC, HPLC and SFC to preparative SFC.
preparative LC making method transfer seamless between different laboratory instrumentation.
Functional group 4.6 x 250mm 10 x 250mm 20 x 250mm 28 x 250mm
Reversed Phase HILIC Shim-pack UC-Diol II Diol 227-32606-02 227-32606-03 227-32606-04 227-32606-05
Shim-pack Scepter
C18 HD-C18 C8 Phenyl PFPP Diol-HILIC Shim-pack UC-Sil II − 227-32607-02 227-32607-03 227-32607-04 227-32607-05
Trifunctional C18 Trifunctional C18 Trifunctional Trifunctional Trifunctional Shim-pack UC-HyP 3-hydroxphenyl 227-32600-02 227-32600-03 227-32600-04 227-32600-05
Ligand Type Trifunctional C8
Generic Purpose Type High Density Type Phenylbutyl Penta uorophenylpropyl Dihydroxypropyl Shim-pack UC-Py Pyridinyl 227-32601-02 227-32601-03 227-32601-04 227-32601-05
Particle Organic Silica Hybrid
Shim-pack UC-PBr Pentabromobenzyl 227-32602-02 227-32602-03 227-32602-04 227-32602-05
Particle Size 1.9 µm, 3 µm, 5 µm
Shim-pack UC-Choles Cholesteryl 227-32603-02 227-32603-03 227-32603-04 227-32603-05
Pore Size 12 nm 8 nm 12 nm
Shim-pack UC-PyE Pyrenylethyl 227-32604-02 227-32604-03 227-32604-04 227-32604-05
End Capping Proprietary None
Shim-pack UC-Triazole Triazole 227-32605-02 227-32605-03 227-32605-04 227-32605-05
pH Range 1 - 12 1 - 10 1 - 8 2 - 10
100% Aqueous Condition Yes No No Yes Yes N/A
USP Classi cation L1 L1 L7 L11 L43 L20
Shim-pack Scepter Analytical Columns A variety of stationary phases: Daicel's chiral columns for SFC
Chemistry C18 HD-C18 C8
Particle Size (µm) Length (mm) ID (mm) 2.1 3 4.6 2.1 3 4.6 2.1 3 4.6 Daicel's CHIRALPAK and CHIRALCEL series chiral columns are
50 227-31012-03 227-31013-01 227-31026-03 227-31027-01 227-31033-03 227-31034-01
75 227-31012-04 227-31013-02 227-31026-04 227-31027-02 227-31033-04 227-31034-02 used worldwide for SFC analysis. They come with a range of
1.9
100 227-31012-05 227-31013-03 227-31026-05 227-31027-03 227-31033-05 227-31034-03
150 227-31012-06 227-31013-04 227-31026-06 227-31027-04 227-31033-06 227-31034-04 stationary phases, to tackle chiral separation of a wide variety
50 227-31014-03 227-31015-01 227-31016-02 227-31028-03 227-31029-01 227-31030-02 227-31035-03 227-31036-01 227-31037-02 of compounds.
75 227-31014-04 227-31015-02 227-31016-03 227-31028-04 227-31029-02 227-31030-03 227-31035-04 227-31036-02 227-31037-03
3 100 227-31014-05 227-31015-03 227-31016-04 227-31028-05 227-31029-03 227-31030-04 227-31035-05 227-31036-03 227-31037-04
150 227-31014-06 227-31015-04 227-31016-05 227-31028-06 227-31029-04 227-31030-05 227-31035-06 227-31036-04 227-31037-05
250 227-31016-06 227-31030-06 227-31037-06
50 227-31017-03 227-31018-01 227-31020-02 227-31021-02 227-31022-01 227-31024-02 227-31038-03 227-31039-01 227-31041-02
75 227-31017-04 227-31018-02 227-31020-03 227-31021-03 227-31022-02 227-31024-03 227-31038-04 227-31039-02 227-31041-03
5 100 227-31017-05 227-31018-03 227-31020-04 227-31021-04 227-31022-03 227-31024-04 227-31038-05 227-31039-03 227-31041-04
150 227-31017-06 227-31018-04 227-31020-05 227-31021-05 227-31022-04 227-31024-05 227-31038-06 227-31039-04 227-31041-05
250 227-31020-06 227-31024-06 227-31041-06
Chemistry Phenyl PFPP Diol-HILIC
Particle Size (µm) Length (mm) ID (mm) 2.1 3 4.6 2.1 3 4.6 2.1 3 4.6
50 227-31063-03 227-31064-01 227-31053-03 227-31054-01 227-31043-03 227-31044-03
75 227-31063-04 227-31064-02 227-31053-04 227-31054-02 227-31043-01 227-31044-01
1.9
100 227-31063-05 227-31064-03 227-31053-05 227-31054-03 227-31043-02 227-31044-02
150 227-31063-06 227-31064-04 227-31053-06 227-31054-04 Column series Stationary phase
50 227-31065-03 227-31066-01 227-31067-02 227-31055-03 227-31056-01 227-31057-02 227-31045-03 227-31046-01 227-31047-02 CHIRALPAK IA/SFC, IA-3/SFC Amylose tris(3,5-dimethylphenylcarbamate)
75 227-31065-04 227-31066-02 227-31067-03 227-31055-04 227-31056-02 227-31057-03 227-31045-04 227-31046-02 227-31047-03
3 100 227-31065-05 227-31066-03 227-31067-04 227-31055-05 227-31056-03 227-31057-04 227-31045-05 227-31046-03 227-31047-04 CHIRALPAK IB/SFC, IB-3/SFC Cellulose tris(3,5-dimethylphenylcarbamate)
150 227-31065-06 227-31066-04 227-31067-05 227-31055-06 227-31056-04 227-31057-05 227-31045-06 227-31046-04 227-31047-05 CHIRALPAK IC/SFC, IC-3/SFC Cellulose tris(3,5-dichlorophenylcarbamate) Polysaccharide derivative
250 227-31067-06 227-31057-06 227-31047-06
50 227-31068-03 227-31069-01 227-31071-02 227-31058-03 227-31059-01 227-31061-02 227-31048-03 227-31049-01 227-31051-02 CHIRALPAK ID/SFC, ID-3/SFC Amylose tris(3-chlorophenylcarbamate) solvent-resistant type
75 227-31068-04 227-31069-02 227-31071-03 227-31058-04 227-31059-02 227-31061-03 227-31048-04 227-31049-02 227-31051-03 CHIRALPAK IE/SFC, IE-3/SFC Amylose tris(3,5-dichlorophenylcarbamate)
5 100 227-31068-05 227-31069-03 227-31071-04 227-31058-05 227-31059-03 227-31061-04 227-31048-05 227-31049-03 227-31051-04
150 227-31068-06 227-31069-04 227-31071-05 227-31058-06 227-31059-04 227-31061-05 227-31048-06 227-31049-04 227-31051-05 CHIRALPAK IF/SFC, IF-3/SFC Amylose tris(3-chloro-4-methylphenylcarbamate)
250 227-31071-06 227-31061-06 227-31051-06 CHIRALPAK AD/SFC, AD-3/SFC Amylose tris(3,5-dimethylphenylcarbamate)
CHIRALPAK AS/SFC, AS-3/SFC Amylose tris[(S)-α-methylbenzylcarbamate]
Shim-pack Scepter Preparative Columns CHIRALPAK AY/SFC, AY-3/SFC Amylose tris(5-chloro-2-methylphenylcarbamate)
Chemistry Length (mm) ID (mm) 10 20 30 Chemistry Length (mm) ID (mm) 10 20 30 CHIRALPAK AZ/SFC, AZ-3/SFC Amylose tris(5-chloro-4-methylphenylcarbamate) Polysaccharide derivative
50 227-31102-01 227-31103-01 50 227-31114-01 227-31115-01 coating type
75 227-31103-02 75 227-31115-02 CHIRALCEL OD/SFC, OD-3/SFC Cellulose tris(3,5-dimethylphenylcarbamate)
C18 100 227-31102-02 227-31103-03 Phenyl 100 227-31114-02 227-31115-03 CHIRALCEL OJ/SFC, OJ-3/SFC Cellulose tris(4-methylbenzoate)
150 227-31101-01 227-31102-03 227-31103-04 150 227-31113-01 227-31114-03 227-31115-04
250 227-31101-02 227-31102-04 227-31103-05 250 227-31113-02 227-31114-04 227-31115-05 CHIRALCEL OX/SFC, OX-3/SFC Cellulose tris(4-chloro-3-methylphenylcarbamate)
50 227-31105-01 227-31106-01 50 227-31111-01 227-31112-01 CHIRALCEL OZ/SFC, OZ-3/SFC Cellulose tris(3-chloro-4-methylphenylcarbamate)
75 227-31106-02 75 227-31112-02
HD-C18 100 227-31105-02 227-31106-03 PFPP 100 227-31111-02 227-31112-03
150 227-31104-01 227-31105-03 227-31106-04 150 227-31110-01 227-31111-03 227-31112-04
250 227-31104-02 227-31105-04 227-31106-05 250 227-31110-02 227-31111-04 227-31112-05
50 227-31108-01 227-31109-01
75 227-31109-02
C8 100 227-31108-02 227-31109-03
150 227-31107-01 227-31108-03 227-31109-04
Solutions for Medicinal Chemistry
250 227-31107-02 227-31108-04 227-31109-05
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