Page 15 - Shimadzu Nexera Series

LabSolutions Chromatography Software

Extract the Smallest of Shoulder Peaks 2.0 mAU 2.0 mAU
[Detection Threshold] = 10 [Detection Threshold] = 10
The i-PeakFinder tool can automatically recognize peaks even in [Detection Threshold of
Unseparated Small Peak] = 0.3
complex chromatograms with high noise, and accounts for 1.5 1.5
baseline drift for higher integration accuracy. Adjustable
parameters in i-PeakFinder, such as peak detection threshold, 1.0 1.0
allow the user to detect smaller peaks.
In addition, the i-PDeA II function can quantify peaks that 0.5 0.5
cannot be completely separated by a column. Separate peaks by
simply specifying the time and wavelength in LabSolutions. 0.0 0.0
17.5 20.0 min 17.5 20.0 min
Shoulder peak detected Smaller peak detected with
automatically parameter adjustment
mAU mAU mAU
200 250 200
Tinuvin
200 150 Irganox
150 144
polystyrene 1010
150 100
100 Tinuvin 144
100 Tinuvin
50 120
50 Irganox 1010
50
Tinuvin 120 0
0 0
16.0 17.0 18.0 19.0 20.0 21.0 22.0 23.0 min 16.0 17.0 18.0 19.0 20.0 21.0 22.0 23.0 min 225 250 275 300 nm
The smaller peak is normally impossible i-PDeA II chromatogram identifies Spectrum analysis with i-PDeA II
to extract the two separate peaks
Application example:
i-PDeA II

Consistent Peak Splitting

Manually setting the baseline for fused mV mV
peaks is time-consuming, and the peaks 4 Main peak 4 Main peak
may be split differently depending on the 3 Impurity 3 Impurity
user. The i-PeakFinder has adjustable
parameters for different analyses, allowing 2 2
the consistent application of the best 1 1
baseline in each situation.
0 0
12.5 15.0 17.5 min 12.5 15.0 17.5 min

Dynamic Range Extension Function for Accurate Calibration

i-DReC is a new analytical method that Area (×10 6 )
significantly extends the dynamic range. It 30 Correlation factor
R = 0.9996726
2
enables the analysis of high-concentration 25
compounds without diluting them, and
ensures a correct calibration curve. 20 Correction
by i-DReC
15
10 Application example:
Original
i-DReC
5
0
0 0.25 0.5 0.75 1
Conc. (g/L)

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