Page 3 - Shimadzu MALDI-8020
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TrueClean™ automated source cleaning                100         80751
            To maintain instrument performance over time, the    90
            MALDI-8020 features wide-bore ion optics - a feature used  80
            on our existing MALDI-TOF products - which minimize the  70
                                                                                          160349
            risk of source contamination over time, providing a robust  60
            platform.                                           % Intensity  50
            To maximize uptime, the system is equipped with TrueClean -  40  46704
            an automated, rapid (<10 min) UV laser-based source  30
            cleaning which can be used to clean the extraction electrode  20  54239
                                                                     40812
            in-situ without breaking instrument vacuum.          10
                                                                 0
                                                                       50000   100000   150000   200000   250000
                                                                                      m/z
                             Polycarbonate monomer from bisphenol A:  Example of higher mass analysis using immunoglobulin A (IgA)
                  1365.1
                 1110.9  1619.3  2127.6   O    OC  = 254.1
                      1873.5
                        5
                         2381.8
                        127.6
                         2
                           2635.9
                         2381
                          8
                             2890.0  3399.2   2127.6   O n  2381.8   Quality as standard
                                3398.2
                1038.7  1443.2  1951.55 2205.7 2713.9  3144.1   2205.7   2309.6   As mass spectrometry moves into clinical laboratories, the
                          2459.8  2970.1
                     1697.3
                        2205.7
                         205.7
                        5
              100  1111.0   24545     100 90                   MALDI-8020 is the perfect choice for researchers developing
              90    1619.5            80
                                                                                        †
              80                      70  2127.9               MALDI-based diagnostic methods . The system is designed
                                      60 50 40  254.1  2382.0
                        2127.9
              % Intensity  60 50  1873.8  2  2636.2  3145.4   30 20 10 0  2100  2150  2200  2250  2300  2350  2400  and manufactured to ISO 9001:2015 and ISO 13485:2016
              70
                        127.9
                                  3653.6
                               3144.4
                         2382
                    1547.4
                          8
              30 40  1039.0  1365.4   8  2382.0  2890.3  3399.5   m/z  quality management standards and is CE compliant.
              20  1294.4    2715.1  3223.4
                       2055.72460.1 2464
              10     1801.6  55.75                             Through the selection of components demonstrating
              0
                           25
                1000  1500  2500  3000  3500  4000  4500  5000  5500  6000
                                 m/z                           improved longevity and performance, and by reducing the
                                                               number of component parts, our engineers have created a
            Polymer analysis: polycarbonate from a CD (green spectrum) and
            polycarbonate standard (orange spectrum).          reliable and robust platform capable of delivering
            Inset: expanded view of the highlighted region.    outstanding performance in a small footprint.
                                                               The MALDI systems are maintained by trained service support
                                                               engineers who form part of the Shimadzu global distribution
                           505.2
             100
                                                               and support network. Routine maintenance is simplified
              90                          505.2   HN  NH
                               100            HN  NH  HN  NH
              80                                NH   HN        thanks to the instrument design, providing our engineers
                               90
                                              HN       NH
              70               80 70                           with easy access to commonly serviced parts.
             % Intensity  60 50  507.3  % Intensity  60 50 40  507.3   Cl  Cl  † For Research Use Only. Not for use in diagnostic procedures.
              40
                               20 30           Chlorhexidine
              30
                               10
              20               0
                                490 492 494 496 498 500 502 504 506 508 510 512 514 516 518 520 522 524
                                           m/z
              10
              0
                  350  400  450  500  550  600  650  700  750  800  850  900  950  1000
                                   m/z
            Analysis of chlorhexidine gluconate in mouthwash solution. Sample
            was prepared with MALDI matrix without any clean-up or dilution.
            Inset: expanded view showing peak at 505.2 m/z.
            Facilitates 21 CFR Part 11 compliance
            Operating under the control of MALDI Solutions™ software,
            the software features a centralized, secure Microsoft ® SQL
            database which can be used to store everything from sample
            lists and acquisition Parameter Sets to acquired MALDI data.
            The system is managed by an Administrator and customizable
            user profiles provide control over access to the database and
            operation of the instrument. Along with a full audit trail, the
            software provides the tools to help achieve 21 CFR part 11
            regulatory compliance.
                                                                                             MALDI-8020
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