Page 2 - Shimadzu MALDI-8020

MALDI-8020: A compact footprint without

compromising on performance

The MALDI-8020 is the latest in a long 100 4187.26{r6343}
line of MALDI-TOF products from 90
80
Shimadzu. This benchtop, linear 70 4188.17{r6184}
MALDI-TOF mass spectrometer delivers % Intensity 60 50 4186.20{r6700}
outstanding performance in a compact 40
4189.22{r7645}
30
footprint, making it an ideal choice for
20 4185.14{r7693} 4190.28{r7463}
today’s increasingly demanding 10 4191.34{r8757}
0
laboratories. 4177 4179 4181 4183 4185 4187 m/z 4189 4191 4193 4195 4197 4199 4201
Example of a 4.2 kDa peptide demonstrating an average resolution
of >5000 FWHM. Resolution, calculated by the software, is shown
Key features: in brackets.
l Linear mode (positive ion) MALDI-TOF
Sample target solutions
l 200 Hz solid-state laser, 355 nm
l Load-lock chamber for fast sample introduction Compatible with the FlexiMass™ series of microscope
slide-format sample targets, these slides provide researchers
l UV laser-based source cleaning (patented)
with options depending on their experimental workflow.
l Small footprint/benchtop design
The individually barcoded, single-use FlexiMass™-DS slides
l Quiet operation (<55 dB)
provide a convenient solution for more routine or defined
workflows. Ready-to-use, these disposable targets eliminate the
need for cleaning and the risk of carryover. Alternatively, the
reusable stainless steel FlexiMass™-SR sample targets provide
a cost-effective, longer-term solution to sample preparation.

C 7 C 8 C 9 C 10 C 11 C 12 C 13 C 14 C 15 C 16 C 17 C 18 C 19 C 20 C 21 C 22 C 23 C 24 C 25 C 26 C 27
H G E G T F T S D L S K Q M E E E A V R L F I E W L K N G G P S S G A P P P S
834.12
100
C 8
90 C 7
80
% Intensity 70 747.08 1405.67 C 19 2094.10 C 21
60
C 13
50
40
C 9 C 11 C 12 C 23 C 24 C 25
30 1277.58 C 14 C 15 C 17 C 20 2393.26
C 10 1435.77 2250.15 2522.33 C 26 C 27
20 1062.45 1536.77 C 16 C 18 C 22 2623.25 3352.13
10 1794.87 2782.14
0
800 1000 1200 1400 1600 1800 2000 2200 2400 2600 2800 3000 3200 3400
m/z
100
90
80
70
% Intensity 60 2651.19
50

40
30 2623.25

20 2752.17 2782.14
10
0

2620 2630 2640 2650 2660 2670 2680 2690 2700 2710 2720 2730 2740 2750 2760 2770 2780 2790 2800 2810
m/z
MALDI-In-Source Decay (MALDI-ISD) spectrum of native Exendin-4
Linear mode instruments have traditionally been the (top panel) showing matched fragment ions consistent with the
instruments of choice in MALDI-TOF-based quality control amino acid sequence. Bottom panel: expanded region of the mass
spectrum showing the isotopically resolved fragment ions.
(QC) and profiling workflows, and the MALDI-8020 is no
exception. Peptides, proteins, polymers or oligonucleotides -
the instrument is capable of delivering the performance
required for QC applications. Research laboratories will also
benefit from the MS capabilities of the instrument through
the rapid mass-measurement of samples.