Page 11 - Shimadzu CLAM-2040

Compatible with Alsachim reagents and Shimadzu methods.
Supports Shimadzu databases for toxicology (TQ or high resolution).
Supports Shimadzu Metabolites Method Package Suite.
Also compatible with third-party reagents.
Compatible with your laboratory developed tests (LDT).

Examples of applications demonstrating the automation by CLAM

Analysis for Voriconazole Antifungal Drug in Plasma (App. No. C146-E464)
Tacrolimus from dry blood spot (App. No. 01-00276-EN)
Choline, TMA, and TMAO in plasma (App. No. 01-00238-EN)
Primary Metabolites in plasma (App. No. 01-00217-EN)
Organic acids in serum (DOI: 10.3390/diagnostics11122195)
First-Line toxicological screening in plasma (DOI: 10.1093/jat/bkaa075)
Antiarrhythmic drugs in plasma (App. No. LAAN-A-LM-E123)
Remdesivir and metabolites in plasma (App. No. C217)
Raltegravir, Dolutegravir, Elvitegravir, and Bictegravir in Plasma (DOI: 10.15369/sujms.32.91)
Uracil and dihydrouracil in plasma (DOI: 10.1016/j.jchromb.2020.122038)
Anticoagulants (NOAC) in plasma (App. No. PO-CON1851E)
Toxicological quantification in whole blood, plasma and urine (DOI: 10.1016/j.cca.2019.03.076)
Mycophenolic acid and metabolite in plasma (poster “Integration of mycophenolic acid and its metabolite analysis
in plasma using LC-MS/MS with full-automated sample preparation")
Drugs of abuse in plasma (DOI: 10.1007/s00216-018-1159-7), in urine (App. No. PO-CON1737E), and in oral fluids
(App. No. PO-CON1753E)
Hydrophilic metabolites in serum and plasma (App. No. PO-CON1720E)
Novel system for analyzing hydrophilic blood metabolites in Plasma (DOI: 10.1016/j.jbiosc.2017.01.015)
Psychoactive drugs in serum, whole blood and urine (App. No. PO-CON1714E)
Metanephrine and normetanephrine in plasma (App. No. PO-CON1751E)
Unbounded amino acids in urine (App. No. PO-CON1733E)
Antibiotics in plasma (poster “Antibiotics in Plasma: A Novel, Seamlessly Automated LC-MS Solution to Increase
Sensitivity, Specificity and Routine Throughput effectiveness”)
Antiepileptics, benzodiazepines, neuroleptics, and TCA in serum (App. No. PO-CON1786)
Neuroleptics drugs in plasma (App. No. PO-CON1785E)
Tricyclic antidepressant drugs in serum (App. No. PO-CON1777E)
Benzodiazepines in serum (App. No. PO-CON1776E)
Antiepileptics drugs in plasma and in serum (App. No. PO-CON1788E and PO-CON1775E)
25-OH Vitamin D2/D3 in Serum (App. No. PO-CON1692E)
Steroids in serum (App. No. PO-CON1691E)

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