Page 254 - Shimadu Consumables Catalog

Appendix I

Syringe filter order guideline
Choosing the right membrane is important. The wrong membrane could cause loss of valuable samples, time and money. Please use below
guideline and chemical compatibility table as reference.
• Naturally hydrophilic, high protein binding, high dirt-loading, surfactant-free and offer the lowest extractables.
Hydrophilic Nylon pH 6-13 • Filtering of general samples and organic solvents.
• Not recommended for use with acids.
• Extremely low protein binding.
Hydrophilic PVDF
(polyvinylidene pH 3-12 • Good chemical compatibility.
• For filtration of non-aggressive aqueous and mild organic solutions, or when maximizing protein recovery is
fluoride)
important.
• Hydrophilic membrane with good solvent resistance.
Hydrophilic RC pH 3-12 • Low protein binding and extractables.
(regenerated cellulose) • Good chemical compatibility with nearly all common HPLC solvents and stable against DMSO.
• Good for general filtration, tissue culture media filtration or life science applications.
Hydrophilic PES pH 3-12 • Low protein binding and extractables.
(polyethersulfone) • Good for life science applications.
• High chemical compatibility.
PTFE pH 1-14 • High temperature resistance.
• Good for filtration of gases, aggressive chemicals, and strong acid.
• Low protein binding
Cellulose Acetate (CA) pH 4-8 • For filtration of aqueous solutions
• Good for applications involving culture media
Mixed Cellulose Ester pH 4-8 • High protein binding
(MCE) • Good for general filtration of aqueous solutions.

Solvent Compatibility:

Solvent MCE CA PES Nylon PVDF PTFE RC
Acetic Acid (glacial) X X O X O O LR
Acetone X X X O X O O
Acetonitrile (ACN) X X X O LR O O
Benzene O O X O O O O
Butyl Alcohol O O O O O O O
Chloroform O X X X O O O
Cyclohexanone X X X O X O O
Dimethyl Sulfoxide (DMSO) X X X O X O O
Ethyl Acetate X X X O O O O
Ethyl Alcohol X O O O LR O O
Formaldehyde X X NI O O O LR
Hexane O O O O O O O
Hydochloric Acid, 1N (HCl) LR LR O LR O O X
Hydochloric Acid, 6N (HCl) LR X LR X LR O X
Hydochloric Acid, 12N (HCl) X X LR X X O X
Hydrogen Peroxide, 3% X O NI O O O X
Isopropyl Alcohol X O O LR O O O
Methanol X O O LR O O O
Nitric Acid, 6N (HNO3) X O O X O O X
Nitric Acid, 12N (HNO3) X X NI X X LR X
Sodium Carbonate (aqueous) O NI NI LR O O NI
Sodium Hydroxide, 3N (NaOH) X X O O O O X
Sulfuric Acid, 6N (H2SO4) LR X LR X LR O LR
Sulfuric Acid, 32N (H2SO4) X X X X LR LR X
Tetrahydrofuran (THF) X X NI O X O O
Toluene O O O O O O O

O: Recommended LR: Limited recommendation X: Not recommended NI: No info